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101
Nano Sized Hydroxyapatite-Polylactic Acid-Vancomycin in Alleviation of Chronic Osteomyelitis
Published 2022-06-01“…The cultured osteoblasts were further divided into control, polyethyleneimine (PEI), and nHA-PLA groups to observe their differences in cell proliferation, mineralization, and migration capacities. And a CO mouse model was constructed to detect the anti-CO effect of nHA-PLA-VAN.Results: nHA-PLA-VAN nanocomposites maintained good stability in different acidic solutions, favoring their long-term preservation in vitro. nHA-PLA extended VAN’s half-life by 6-times. …”
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102
Developing amyloid-β chaperone lipocalin-type prostaglandin D synthase protein as a magnetic resonance active early diagnostic tool
Published 2020“…To this end, we have shown here that L-PGDS protein has great outlook as a diagnostic agent for early identification of AD hallmarks in disease-prone populations, and potential as a therapeutic intervention.…”
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Thesis-Doctor of Philosophy -
103
An Optimized Method of Metabolite Extraction from Formalin-Fixed Paraffin-Embedded Tissue for GC/MS Analysis.
Published 2015-01-01“…Nevertheless, we proved applicability of FFPE specimens for non-targeted GS/MS-based profiling of tissue metabolome, which is of great importance for feasibility of metabolomics studies using retrospective clinical material.…”
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104
A quantitative technique to analyze and evaluate microstructures of skin hair follicles based on mueller matrix polarimetry
Published 2022“…The results shown in this study suggest that the technique based on Mueller matrix microscopy can realize automatically hair follicle identification, detection, and quantitative evaluation. It has great potential in skin structure-related studies and clinical dermatological applications.…”
Journal article -
105
Immunochemical activity of <i>Yersinia pseudotuberculosis</i> ompF and ompC porins evaluated by optical trapping
Published 2022-12-01“…Study of features for interacting antigen-antibody system is of great importance for developing new modern tools for diagnostics and therapy of infectious diseases. …”
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106
Sustained notch signaling inhibition with a gamma-secretase inhibitor prevents traumatic heterotopic ossification
Published 2023-09-01“…Methods: We firstly detected the expressions of Notch target genes in both mouse and human THO samples with quantitative RT-PCR and immunohistochemistry (IHC). …”
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107
Characterisation of the expression and function of the GM-CSF receptor alpha-chain in mice.
Published 2007“…The ability to detect GM-CSF receptor expression in experimental studies should greatly facilitate the analysis of its role in immune pathologies.…”
Journal article -
108
Assessing the Attractiveness of Three Baits for Roof Rats in California Citrus Orchards
Published 2021-11-01“…The identification of baits that are both attractive and readily available would be of great assistance for monitoring changes in roof rat numbers within agricultural fields. …”
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109
The use of CpG-free plasmids to mediate persistent gene expression following repeated aerosol delivery of pDNA/PEI complexes.
Published 2012“…Aerosol gene therapy offers great potential for treating acquired and inherited lung diseases. …”
Journal article -
110
Data-Glove-Based Hand Gesture Recognition System Using Flex Sensors And An Imu Sensor
Published 2017“…With the great expansion of computer technology, Human-Computer Interaction (HCI) is required to be more effective. …”
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Monograph -
111
Quantitation of Tissue Amyloid via Fluorescence Spectroscopy Using Controlled Concentrations of Thioflavin-S
Published 2023-06-01“…In this study, we developed an optimized ThS staining protocol for the sensitive detection of β-amyloids in the widely used 5xFAD Alzheimer’s mouse model. …”
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Article -
112
Ceritinib is a novel triple negative breast cancer therapeutic agent
Published 2022-06-01“…Combination therapy of these drugs were investigated using AR positive breast cancer mouse xenograft models. Also, combination treatment of ceritinib and paclitaxel investigated using AR− and AR low mouse xenograft and patient derived xenograft models. …”
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113
Simple Plasma Test Based on a MoSe2 SERS Platform for the Specific Diagnosis of Alzheimer’s Disease
Published 2023-05-01“…In general, the MoSe2 SERS detection platform can well detect the concentration of BD-tau in mouse plasma samples, showing great potential in specific recognition of AD among neurodegenerative diseases.…”
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114
Investigation of early molecular alterations in tauopathy with generative adversarial networks
Published 2023-01-01“…Abstract The recent advances in deep learning-based approaches hold great promise for unravelling biological mechanisms, discovering biomarkers, and predicting gene function. …”
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115
Ciliated Cells Express a Novel Pattern of Brain-Derived Neurotrophic Factor in Allergic Rhinitis
Published 2023-06-01“…The expression level of BDNF and IL-4/5/13 were detected by RT-PCR. The expressions of BDNF (in serum and NAL fluid), and total-IgE, ovalbumin sIgE (in serum) were detected by ELISA.Results: We found that MFI of BDNF in AR group’s ciliated cells was obviously lower than that in the control group, and a negative correlation was discovered between MFI and VAS score. …”
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116
Application of a Novel One-Side Cell Quartz Crystal Microbalance Immunosensor in the Determination of Alpha-Fetoprotein from Human Serum
Published 2023-05-01“…The rapid and accurate detection of alpha-fetoprotein (AFP) levels is of great significance for the diagnosis and later treatment evaluation of liver cancer. …”
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117
Improved localization of cellular membrane receptors using combined fluorescence microscopy and simultaneous topography and recognition imaging.
Published 2010“…The combination of fluorescence microscopy and atomic force microscopy has a great potential in single-molecule-detection applications, overcoming many of the limitations coming from each individual technique. …”
Journal article -
118
Gene Expression over Time during Cell Transformation Due to Non-Genotoxic Carcinogen Treatment of Bhas 42 Cells
Published 2022-03-01“…This assay offers the great advantage of enabling the phenotypic detection of oncotransformation. …”
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119
Systemic delivery of antisense oligoribonucleotide restores dystrophin expression in body-wide skeletal muscles.
Published 2005“…Antisense oligonucleotide-mediated alternative splicing has great potential for treatment of Duchenne muscular dystrophy (DMD) caused by mutations within nonessential regions of the dystrophin gene. …”
Journal article -
120
Noninvasive Near-infrared Imaging of Fluorochromes within the Brains of Live Mice: An In Vivo Phantom Study
Published 2006-07-01“…Near-infrared fluorescence (NIRF) imaging has great potential for studying physiological and pathophysiological processes noninvasively in several locations of the body. …”
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Article