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121
Drug repurposing: insights into the antimicrobial effects of AKBA against MRSA
Published 2024-01-01“…In addition, the effective antimicrobial effect was verified in vivo in a mouse model. And no detectable in vivo toxicity was found. …”
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122
The isolation and characterization of orbiviruses from ticks (ixodes uriae)
Published 1984“…The viruses replicated in suckling mouse brain, chick embryo fibroblasts, Vero and BHK-21 cells, but not in Xenopus cells. …”
Thesis -
123
Automated whole-cell patch-clamp electrophysiology of neurons in vivo
Published 2013“…Whole-cell patch-clamp electrophysiology of neurons is a gold-standard technique for high-fidelity analysis of the biophysical mechanisms of neural computation and pathology, but it requires great skill to perform. We have developed a robot that automatically performs patch clamping in vivo, algorithmically detecting cells by analyzing the temporal sequence of electrode impedance changes. …”
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124
Cell-Membrane Biomimetic Indocyanine Green Liposomes for Phototheranostics of Echinococcosis
Published 2022-05-01“…In-vitro and in-vivo studies reveal that biomimetic Lipo-ICG with high biocompatibility can achieve in-vivo near-infrared fluorescence imaging and phototherapy of echinococcosis in mouse models. Our research is the first to apply bionanomaterials to the phototherapy of echinococcosis, which provides a new standard for the convenient and noninvasive detection and treatment of zoonotic diseases.…”
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125
Coumarin-Modified CQDs for Biomedical Applications—Two-Step Synthesis and Characterization
Published 2020-10-01“…Waste biomass such as lignin constitutes a great raw material for eco-friendly carbon quantum dots (CQDs) synthesis, which find numerous applications in various fields of industry and medicine. …”
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126
Facile assembly of upconversion nanoparticle-based micelles for active targeted dual-mode imaging in pancreatic cancer
Published 2018-01-01“…Furthermore, we successfully concluded that CD326-conjugated micelles endowed promising active targeting ability by conducting dual-mode imaging in human pancreatic cancer xenograft mouse model. Conclusions With good biocompatibility and excellent imaging properties of the micelles, our results uncover efficient active homing of those micelles after intravenous injection, and undoubtedly demonstrate the as-obtained micelles holds great potential for early pancreatic cancer diagnosis in the future and would pave the way for the following biomedical applications.…”
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127
Development of an electrooculogram (EOG) based virtual keyboard
Published 2014“…One of the work is using EOG signal to control a mouse cursor. Research has shown that EOG is better than EEG when it comes to man and machine interaction. …”
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128
CircRNA Expression Profile during Yak Adipocyte Differentiation and Screen Potential circRNAs for Adipocyte Differentiation
Published 2020-04-01“…Furthermore, we analyzed the homology among yak, human and mouse circRNAs and found that 3536 yak circRNAs were homologous to human and mouse circRNAs. …”
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129
Natural Killer Cells and Type 1 Innate Lymphoid Cells in Hepatocellular Carcinoma: Current Knowledge and Future Perspectives
Published 2021-08-01“…In addition, they are equipped with a wide range of receptors, allowing them to detect “stressed cells’ such as cancer cells. Our understanding of the role of innate lymphoid cells in hepatocellular carcinoma (HCC) is growing owing to the development of mouse models, the progress in immunotherapeutic treatment and the recent use of scRNA sequencing analyses. …”
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130
Dynamics of 8G12 competitive antibody in “prime-boost” vaccination of Hepatitis E vaccine
Published 2017-06-01“…Total anti-HEV antibody has been used to reflect vaccine induced immune response in clinical trials for the lack of robust HEV neutralizing antibody detection methods. In this study, we applied a broad neutralizing mouse monoclonal antibody 8G12 to develop a competitive ELSIA assay and quantified 8G12 competitive antibody (8G12-like antibody) in serum samples. …”
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131
Assessing the spatiotemporal interactions of mesopredators in Sumatra’s tropical rainforest
Published 2018“…Clouded leopard was more nocturnal and, consequently, had higher temporal overlap with the more nocturnal prey species, such as porcupine and mouse deer, whereas the more diurnal golden cat had higher overlap with the strictly diurnal great argus pheasant. …”
Journal article -
132
A new gene-scoring method for uncovering novel glaucoma-related genes using non-negative matrix factorization based on RNA-seq data
Published 2023-06-01“…Findings showed our NMF method significantly improved the enrichment detection of glaucoma genes. The application of NMF with the scoring method showed great promise in the identification of marker genes for glaucoma.…”
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133
Characterization of the Human Papillomavirus 16 Oncogenes in K14HPV16 Mice: Sublineage A1 Drives Multi-Organ Carcinogenesis
Published 2022-10-01“…This study aimed to determine the HPV16 variant and sublineage present in the K14HPV16 mouse model. This information can be considered of great importance to further enhance this K14HPV16 model as an essential research tool and optimize its use for basic and translational studies. …”
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134
Triptolide enhances carboplatin-induced apoptosis by inhibiting nucleotide excision repair (NER) activity in melanoma
Published 2023-06-01“…Cell viability, migration, invasion, apoptosis, and DNA damage were detected by conventional methods. The rate-limiting proteins of the NER pathway were quantitated using PCR and Western blot. …”
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135
HEX expression and localization in normal mammary gland and breast carcinoma
Published 2006-07-01“…</p> <p>Results</p> <p>In normal breast HEX was detected both in the nucleus and in the cytoplasm. …”
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136
A Simple ICT-Based Fluorescent Probe for HOCl and Bioimaging Applications
Published 2023-07-01“…Expectantly, the fluoxetine-induced liver injury model is successfully established, and probe <b>1</b> has been used for detecting the fluctuation of ClO<sup>−</sup> levels in the mouse model of fluoxetine-induced liver injury. …”
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137
Development and validation of a PCR-free nucleic acid testing method for RNA viruses based on linear molecular beacon probes
Published 2022-06-01“…Conclusions The proposed RNA virus probe could be used as a PCR-free, cost-effective, and rapid point-of-care (POC) diagnostic platform for target RNA virus detection, holding great potential for the convenient monitoring of different RNA viruses for early mass virus screening. …”
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138
Direct administration of mesenchymal stem cell‐derived mitochondria improves cardiac function after infarction via ameliorating endothelial senescence
Published 2023-01-01“…Replacing injured mitochondria with healthy mitochondria to restore mitochondrial bioenergy in myocardium holds great promise for cardioprotection after infarction. …”
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139
Indocyanine Green and Arginine-Glycine-Aspartic Acid Complex Used in Intraoperative Visualization during Resection of Bladder Tumour
Published 2019-01-01“…In the connection, it is proposed to use a highly sensitive bladder cancer detection method, which also detects residual tumours. …”
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140
Efficient Mining of Anticancer Peptides from Gut Metagenome
Published 2023-09-01“…Moreover, the therapeutic potential of the two most promising peptides in a mouse xenograft cancer model is evaluated. Encouragingly, the peptides exhibit effective tumor inhibition without any detectable toxic effects. …”
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