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    教育體制改革下行政組織的轉型:晚清省級教育行政制度的再造 Educational Administration Transformation as Educational System Reform: Reconstructing the Provincial Administration System of the Education Department... by 周愚文 Yu-Wen Chou

    Published 2022-03-01
    “…In addition, the Qing government reorganized its provincial administration of the education department. As a result, three critical problems arose. …”
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    The influence of CYP3A5 polymorphisms on haloperidol treatment in patients with alcohol addiction by Zastrozhin MS, Grishina EA, Ryzhikova KA, Smirnov VV, Savchenko LM, Bryun EA, Sychev DA

    Published 2017-12-01
    “…Mikhail Sergeevich Zastrozhin,1,2 Elena Anatolievna Grishina,1 Kristina Anatolievna Ryzhikova,1 Valery Valerievich Smirnov,3 Ludmila Mikhailovna Savchenko,1 Evgeny Alekseevich Bryun,1,2 Dmitry Alekseevich Sychev1 1Russian Medical Academy of Continuous Professional Education, Ministry of Health of the Russian Federation, 2Moscow Research and Practical Centre on Addictions, Moscow Department of Healthcare, 3National Research Center Institute of Immunology, Federal Medical-Biological Agency, Moscow, Russia Background: Isoenzymes CYP2D6 and CYP3A4, the activity of which varies widely, are involved in metabolism of haloperidol and may influence its profile of efficacy and safety.Objective: The primary aim of this study was to estimate the relationship between CYP3A5 gene polymorphism, activity of the CYP3A isoenzyme, and the risk of development of adverse drug reactions by haloperidol in patients with alcohol abuse.Methods: Sixty-six male alcohol-addicted patients participated in the study. …”
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