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Sex Hormones Promote Opposite Effects on ACE and ACE2 Activity, Hypertrophy and Cardiac Contractility in Spontaneously Hypertensive Rats.
Published 2015-01-01“…Orchiectomy decreased the activity of these enzymes and hypertrophy, while ovariectomy increased hypertrophy and ACE2, but did not change ACE activity. For cardiac function, the male sham group had a lower +dP/dt than the female sham group. …”
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Genetic determinants of COVID-19 severity and mortality: ACE1 Alu 287 bp polymorphism and ACE1, ACE2, TMPRSS2 expression in hospitalized patients
Published 2025-01-01“…Evidence indicates that ACE1 may influence ACE2 expression. This study aims to determine whether ACE1, ACE2, and TMPRSS2 mRNA expression levels, along with the ACE1 Alu 287 bp polymorphism (rs4646994), contribute to the severity and mortality of COVID-19. …”
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[Indications for ACE inhibitors in the postinfarct period]
Published 1994“…Three days after myocardial infarction hemodynamically stable patients with heart failure may be treated with ACE-inhibitors (AIRE study). …”
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Indication of ACE-inhibitors post-myocardial infarction
Published 1994“…Three days after myocardial infarction hemodynamically stable patients with heart failure may be treated with ACE-inhibitors (AIRE study). …”
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Fatal Neurodissemination and SARS-CoV-2 Tropism in K18-hACE2 Mice Is Only Partially Dependent on hACE2 Expression
Published 2022-03-01“…Intranasally inoculated transgenic mice expressing human angiotensin-converting enzyme 2 under the cytokeratin 18 promoter (K18-hACE2) represent a lethal model of SARS-CoV-2 infection. …”
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COMBINED ANTIHYPERTENSIVE THERAPY: FOCUS ON A FIXED-DOSE COMBINATION OF AN ACE INHIBITOR AND A DIURETIC
Published 2010-10-01“…The study aimed to assess the effectiveness and safety of a fixed-dose combination of an ACE inhibitor (losartan) and a diuretic (hydrochlorothiazide) in patients with arterial hypertension (AH) and high or very high cardiovascular risk. …”
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Delayed-onset Angioedema Following a Snakebite in a Patient on ACE Inhibitors: A Case Report
Published 2023-08-01Get full text
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The Effect of ACE Inhibitors/ARBs Withdrawal on the Risk of Postoperative Complications in Abdominal Surgery
Published 2023-10-01“…A significant proportion of patients undergoing non-cardiac surgery receive therapy with angiotensin converting enzyme (ACE) inhibitors/angiotensin II receptor blockers (ARBs), which are usually prescribed for treatment of arterial hypertension and CHF. …”
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PREVENTION OF ANTRACYCLIN ANTIBIOTIC DOXORUBICIN СARDIOTOXICITY: A ROLE OF ACE-INHIBITOR PERINDOPRIL
Published 2014-07-01Get full text
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Isolated Laryngeal Angioedema in a Patient with Long-term ACE Inhibitor Use: A Case Report
Published 2024-01-01“…Introduction: Angiotensin converting enzyme (ACE) inhibitor-associated angioedema is the most common cause of angioedema seen in the emergency department (ED) and can be associated with a high morbidity. …”
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Modulation of the pharmacokinetics of soluble ACE2 decoy receptors through glycosylation
Published 2024-09-01“…The Spike of SARS-CoV-2 recognizes a transmembrane protease, angiotensin-converting enzyme 2 (ACE2), on host cells to initiate infection. …”
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ACE Inhibitor-Induced Angioedema following Cervical Spine Surgery
Published 2017-01-01“…However, ACE inhibitors induced angioedema after cervical surgery is a rare condition. …”
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Knockout of ACE-N facilitates improved cardiac function after myocardial infarction
Published 2023-03-01“…Wild-type (WT) and ACE-N knockout (ACE-NKO) mice were subjected to MI by ligating the left anterior descending artery and treated with vehicle or Ac-SDKP (1.6 mg/kg/day, s.c.) for 5 weeks, after which echocardiography was performed and left ventricles (LV) were harvested for histology and molecular biology studies. …”
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ACE gene deletion/deletion polymorphism may be a protective factor for respiratory distress in preterm infants
Published 2007-01-01“…The ACE I/I genotype is associated with an increased risk of respiratory disorders among premature infants and the D/D genotype is a protective factor for respiratory disorders, but these infants with ACE D/D genotype might be at risk for the development of cardiovascular disorders later in life. …”
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Angiotensin-Converting Enzyme (ACE) genetic variation and longevity in Peruvian older people: a cross-sectional study
Published 2020-04-01“…Aim: To describe the age distribution of the ACE polymorphism in a convenience sample of Peruvian older people. …”
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