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Solar cycle changes in the geo-effectiveness of small-scale solar wind turbulence measured by Wind and ACE at 1 AU
Published 2007-06-01“…Wind spacecraft measurements during 1995 to 1998 and ACE spacecraft measurements during 1997 to 2005 were used to characterise the evolution of small-scale (~1 min to 2 h) fluctuations in the solar wind speed <I>v<sub>sw</sub></I>, magnetic energy density <I>B</I><sup>2</sup>, and solar wind ε parameter, in the context of large-scale (~1 day to years) variations. …”
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Satellite remote sensing of Asian aerosols: a case study of clean, polluted, and Asian dust storm days
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Angiotensin-Converting Enzyme (ACE) Inhibitors May Moderate COVID-19 Hyperinflammatory Response: An Observational Study with Deep Immunophenotyping
Published 2022-01-01“…From the analysis of gene expression profiles, we observed a noticeable up-regulation in the expression of 1L1R2 (an anti-inflammatory receptor) and RETN (an immunosuppressive marker) genes in monocytes among prior users of ACE inhibitors. …”
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Clinical efficacy of a benazepril and spironolactone combination in dogs with congestive heart failure due to myxomatous mitral valve disease: The BEnazepril Spironolactone STudy (...
Published 2021-07-01“…Hypothesis/Objectives To determine if a mineralocorticoid receptor antagonist (spironolactone) is beneficial and safe in CHF due to myxomatous mitral valve disease (MMVD) of varying severity, we hypothesized that, when combined with furosemide, a combination product (S+BNZ) containing the ACE inhibitor (ACE‐I), benazepril, and spironolactone, would be superior to benazepril alone. …”
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Standardization of a fluorimetric assay for the determination of tissue angiotensin-converting enzyme activity in rats
Published 2000-07-01“…Enzyme activity was stable when the homogenates were stored at -20o or -70oC for at least 30 days. These results indicate a condition whereby ACE activity can be easily and efficiently assayed in rat tissue samples homogenized in BB using a fluorimetric method with Hip-His-Leu as a substrate.…”
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Exercise Induced-Cytokines Response in Marathon Runners: Role of ACE I/D and BDKRB2 +9/-9 Polymorphisms
Published 2022-09-01“…The aim of the study was to evaluate the role of ACE I/D and BDKRB2 +9/−9 polymorphism on exercise-induced cytokine response. …”
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Phase I dose-escalation study to assess the safety, tolerability, pharmacokinetics and pharmacodynamics of an inhaled recombinant human ACE2
Published 2024-02-01“…Background APN01 is a soluble recombinant human angiotensin-converting enzyme 2 (rhACE2), a key player in the renin–aldosterone–angiotensin system (RAAS). …”
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Cell aggregation mediated by ACE2 deletion in Candida auris modulates fungal colonization and host immune responses in the skin
Published 2024-11-01“…Our results indicate that mice infected with ace2Δ strain had significantly lower fungal load after 3 and 14 days post-infections compared to the non-aggregative wild-type and the ACE2 reintegrated strain. …”
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Omicron XBB.1.5 subvariant causes severe pulmonary disease in K18-hACE-2 mice
Published 2024-10-01“…Intranasal XBB.1.5 infection resulted in 100% mortality in K18-hACE2 mice. High virus titers were detected in the lungs on days 3 and 5 after infection. …”
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Identification of potential inhibitors of SARS-CoV-2 S protein–ACE2 interaction by in silico drug repurposing [version 2; peer review: 2 approved]
Published 2021-11-01“…Results: This research yielded 40 drugs identified as a potential inhibitor of RBD S1-ACE2 interaction. …”
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Potassium Intake Prevents the Induction of the Renin-Angiotensin System and Increases Medullary ACE2 and COX-2 in the Kidneys of Angiotensin II-Dependent Hypertensive Rats
Published 2019-10-01“…In this report we evaluate the expression of AGT, ACE, medullary prorenin/renin, ACE2, kallikrein and cyclooxygenase-2 (COX-2) in Ang II-infused rats fed with high K+ diet (2%) for 14 days. …”
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Neuroprotective Effects of Casein-Derived Peptide Met-Lys-Pro (MKP) in a Hypertensive Model
Published 2020-08-01“…For long term evaluation, rats were fed either a diet containing CH-3 or normal diet. The survival rate of SHRSP rats was significantly improved by intake of CH-3 for 181 days. …”
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COVID-19: A New Horizon in Congenital Heart Diseases
Published 2021-12-01“…The median interval between surgery and COVID-19 assessment was 305 days (IQR = 215–400). In addition, 67 (32%) patients used angiotensin receptor blocker (ARB)/angiotensin-converting enzyme (ACE) inhibitor (spironolactone and/or captopril). …”
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Sweet Memories or Not? A Comparative Study on Cognitive Impairment in Diabetes Mellitus
Published 2022-02-01“…IntroductionType 2 Diabetes Mellitus is a modern-day epidemic and dementia has been declared as a global challenge. …”
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The high efficiency protective effectiveness of a newly isolated myoviruses bacteriophage vB_AceP_PAc in protecting mice from Aeromonas caviae infection in mice
Published 2025-03-01“…This study involved the isolation and purification of a novel myoviruses phage, vB_AceP_PAc, from a drug-resistant bacterial strain Aeromonas caviae. …”
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