Genetic and observational associations of nuclear magnetic resonance-measured lipid-related traits and atherosclerotic cardiovascular mortality in the Mexico City Prospective Study by Wang, Y

“…This approach could help alleviate the growing burden of ASCVD and related chronic diseases on a large scale, improving overall population well-being.…”

Anhydrous weight loss kinetics model development for torrefied green waste by Nur Ashikin, Jamin, Noor Asma Fazli, Abdul Samad, Suriyati, Saleh

“…One of the compositions of municipal solid waste (MSW) is green waste (GW) that collected from landscaping, garden, yard and trimming waste. GW has potential in becoming a biomass feedstock, but poses some drawbacks such as high moisture content, low heating value, high O/C and H/C ratios. …”
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The Urban Infrastructure of Care: Planning for Equitable Social Reproduction by Binet, Andrew, Houston-Read, Rebecca, Gavin, Vedette, Baty, Carl, Abreu, Dina, Genty, Josée, Tulloch, Andrea, Reid, Azan, Arcaya, Mariana

“…We recommend strategies for integrating care as an outcome of concern into planning decisions and practices and for making coordinated investments in urban infrastructures of care that seek to more equitably distribute resources for and burdens of care in cities.…”
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Selective targeting of MYC mRNA by stabilized antisense oligonucleotides by Gill, Taylor, Wang, Haichuan, Bandaru, Raj, Lawlor, Matthew, Lu, Chenyue, Nieman, Linda T, Tao, Junyan, Zhang, Yixian, Anderson, Daniel G, Ting, David T, Chen, Xin, Bradner, James E, Ott, Christopher J

“…In a MYC-induced model of hepatocellular carcinoma, MYCASO treatment decreases MYC protein levels within tumors, decreases tumor burden, and improves overall survival. MYCASOs represent a new chemical tool for in vitro and in vivo modulation of MYC activity, and promising therapeutic agents for MYC-addicted tumors.…”
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Development of quorum-sensing circuits for metabolic flux control in Escherichia coli by Dinh, Christina V.

“…To address major limitations in the naringenin and salicylic acid pathways, one module was used to delay transcription of key heterologous genes to overcome enzyme inhibition and growth burden while the second module controlled expression of CRISPRi components to silence competing endogenous pathways. …”
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Rapid prediction of conformationally-dependent DFT-level descriptors using graph neural networks for carboxylic acids and alkyl amines by Haas, Brittany C, Hardy, Melissa A, Sowndarya S. V., Shree, Adams, Keir, Coley, Connor W, Paton, Robert S, Sigman, Matthew S

“…Descriptor libraries can be precomputed agnostic of application to reduce the computational burden of data-driven reaction development. However, as one often applies these models to evaluate novel hypothetical structures, it would be ideal to predict the descriptors of compounds on-the-fly. …”
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Active mobility device parking characteristics at MRT stations by Ng, Yi Shien

“…In this project, three Mass Rapid Transit (MRT) stations – Boon Lay, Lakeside and Chinese Garden – were selected to investigate AMD parking characteristics. …”
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Stability improvement for three-phase grid-connected converters through impedance reshaping in quadrature-axis by Fang, Jingyang, Li, Xiaoqiang, Li, Hongchang, Tang, Yi

“…To resolve the instability issue caused by PLLs, this paper proposes an impedance controller for reshaping the q-axis impedance into a positive resistance in the low-frequency band. Without any extra burden on system hardware, the proposed controller can easily be implemented by directly relating the q-axis voltage to the q-axis current reference. …”
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Robust fuzzy model predictive control of discrete-time Takagi–Sugeno systems with nonlinear local models by Teng, Long, Wang, Youyi, Cai, Wenjian, Li, Hua

“…For model predictive control of T-S fuzzy systems, the online computational burden is even worse. Especially for complex systems with severe nonlinearities, parametric uncertainties, and disturbances, existing model predictive control of T-S fuzzy systems usually leads to a very conservative solution or even no solution in some occasions. …”
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Living wishes : a communication campaign encouraging Singapore residents aged 35 to 59 to initiate Advance Care Planning discussions with their elderly parents by Chong, Charlotte Wen Wei, Gouw, Emily Shu Hui, Lee, Phyllis Zhi Ning, Tan, Raelynn Zhi Xuan

“…This brings about significant issues, such as the loss of patient autonomy and increased burden on one’s family members when it comes to making important decisions about one’s EOL care. …”
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An efficient differential evolution with fitness-based dynamic mutation strategy and control parameters by Gupta, Shubham, Su, Rong

“…This algorithm avoids the burden of selecting appropriate mutation strategy and control parameters and tries to maintain an appropriate balance between diversity and convergence. …”
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The anxious chronicles: visualising my anxiety through acceptance commitment therapy (ACT) as well as humour and satire by Dugang, Pahang Chelsea Ro-Ann

“…I also incorporate illustrations depicting various perspectives on anxiety, as I strive to convey the idea that anxiety is not a burden to get rid of but rather a companion to be understood and nurtured. …”
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Unconventional exhibitions of desire. by Ng, Hwei Yun.

“…In contrast, physicality may seem like a burden to the imagination, when we see Jordan and city dwellers fantasizing about the lack of gravity and being able to leave your body behind to pursue other desires. …”
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A Chronic Autoimmune Dry Eye Rat Model with Increase in Effector Memory T Cells in Eyeball Tissue by Hou, Aihua, Bose, Tanima, Chandy, Kanianthara George, Tong, Louis

“…Dry eye disease is a very common condition that causes morbidity and healthcare burden and decreases the quality of life. There is a need for a suitable dry eye animal model to test novel therapeutics to treat autoimmune dry eye conditions. …”
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Barriers and leverage points for seeing alcohol differently in integrated care systems in England: a senior stakeholder interview study by Madden, Mary, Stewart, Duncan, McCambridge, Jim

“…Nationally, alcohol has received limited attention in National Health Service (NHS) strategic decision-making relative to its burden of harm, which varies considerably in localities. …”
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Agamben's understanding of time and its implications for Christology by Wright, O

“…In his most recent and intriguing publications however (such as Pulcinella, The Kingdom and the Garden, and The Fire and the Tale), those questions are freshly inflected. …”

Determinants of underdiagnosis of COPD in national and international surveys by Lamprecht, B, Soriano, JB, Studnicka, M, Kaiser, B, Vanfleteren, LE, Gnatiuc, L, Burney, P, Miravitlles, M, García-Rio, F, Akbari, K, Ancochea, J, Menezes, AM, Perez-Padilla, R, Montes de Oca, M, Torres-Duque, CA, Caballero, A, González-García, M, Buist, S

“…<p><strong>Background:</strong> COPD ranks within the top three causes of mortality in the global burden of disease, yet it remains largely underdiagnosed. …”

Identifying antifungal resistance mechanisms and modes of action using SAturated Transposon Analysis in Yeast (SATAY) by Karadzas, M

“…<p>Fungal pathogens are a serious burden for public health and global food security. …”

The role of CD1a in dengue infection by Yang, J

“…It causes a heavy healthcare burden globally, while treatment and prevention approaches are limited. …”

Factors influencing macrophage phagocytosis and killing of Gram negative bacteria by Kurzyp, K

“…<p>Gram negative infections pose a significant burden on human health. <em>Escherichia coli</em> causes blood stream infection and sepsis, while <em>Neisseria gonorrhoeae</em> is a leading causes of pelvic inflammatory disease, infertility and ectopic pregnancy. …”