Clinical outcomes of patients with unsuccessful mechanical thrombectomy versus best medical management of medium vessel occlusion stroke in the middle cerebral artery territory by Faizy, TD, Yedavalli, V, Salim, HA, Lakhani, DA, Musmar, B, Adeeb, N, Essibayi, MA, Daraghma, M, El Naamani, K, Henninger, N, Sundararajan, SH, Kuhn, AL, Khalife, J, Ghozy, S, Scarcia, L, Yeo, LL, Tan, BY, Regenhardt, RW, Heit, JJ, Cancelliere, NM, Rouchaud, A, Fiehler, J, Sheth, SA, Puri, AS, Dmytriw, AA

Publishers’ and journals’ instructions to authors on use of generative artificial intelligence in academic and scientific publishing: bibliometric analysis by Ganjavi, C, Eppler, MB, Pekcan, A, Biedermann, B, Abreu, A, Collins, GS, Gill, IS, Cacciamani, GE

“…Lack of standardization places a burden on authors and could limit the effectiveness of the regulations. …”

Personalised modelling of geographic movements in depression by Palmius, N

“…One way to improve the care that patients receive, and reduce the burden on the healthcare system, is to monitor the health of patients over time. …”

Intersection between individual, household, environmental and system level factors in defining risk and resilience for children in Kenya’s ASAL: A qualitative study by Chongwo, EJ, Aoko, B, Kaniala, M, Esala, M, Magoma, P, Njoroge, E, Nyamanya, S, Marangu, J, Khamis, A, Ng’asike, J, Huizink, AC, Abubakar, A

“…Systematic documentation of factors influencing child outcomes is crucial for understanding the overall burden, informing policy and implementing targeted interventions. …”

Ten pressure points in primary care during COVID-19: findings from an international narrative review by Dykgraaf, SH, Parkinson, A, Wright, M, Wong, WCW, Desborough, J, Ball, L, Sturgiss, E, Dut, GM, Barnes, K, Butler, D, Davis, S, Douglas, K, Kendir, C, Martin, D, Marten, R, Rouleau, K, Barkley, S, de Toca, L, Kidd, M

“…This secondary analysis of data from an integrative systematic review across international PC settings aimed to identify and describe burdens and challenges experienced by PCPs and PC services in the context of their contributions to COVID-19 pandemic responses. …”

Implementing strategies to improve uptake of patient-reported outcome measures (PROMs) in gender-affirming care: a mixed-methods implementation study by Kamran, R, Jackman, L, Goodwin, C, Laws, A, Stepney, M, Harrison, C, Jain, A, Rodrigues, J

“…Response rates to PROM completion dropped as the study progressed, as the burden of reviewing implementation strategies increased. …”

Radiotherapy and theranostics: a Lancet Oncology Commission by Abdel-Wahab, M, Giammarile, F, Carrara, M, Paez, D, Hricak, H, Ayati, N, Li, JJ, Mueller, M, Aggarwal, A, Al-Ibraheem, A, Alkhatib, S, Atun, R, Bello, A, Berger, D, Delgado Bolton, RC, Buatti, JM, Burt, G, Bjelac, OC, Cordero-Mendez, L, Dosanjh, M, Eichler, T, Fidarova, E, Gondhowiardjo, S, Gospodarowicz, M, Grover, S, Hande, V, Harsdorf-Enderndorf, E, Herrmann, K, Hofman, MS, Holmberg, O, Jaffray, D, Knoll, P, Kunikowska, J, Lewis, JS, Lievens, Y, Mikhail-Lette, M, Ostwald, D, Palta, JR, Peristeris, P, Rosa, AA, Salem, SA, Dos Santos, MA, Sathekge, MM, Shrivastava, SK, Titovich, E, Urbain, J-L, Vanderpuye, V, Wahl, RL, Yu, JS, Zaghloul, MS, Zhu, H, Scott, AM

“…In this Commission, we propose actions and investments that could enhance access to radiotherapy and theranostics worldwide, particularly in LMICs, to realise health and economic benefits and reduce the burden of cancer by accessing these treatments.…”

Self-reported pain and osteoarthritis of the hip and spine in retired elite rowers by Baynham-Williams, M

“…<p><b>Background and Aim:</b> Pain in the hip and spine presents a large burden to athletes competing in rowing. Previous injury is a risk factor for the development of osteoarthritis (OA) in later life. …”

Malaria elimination challenges in countries approaching the last mile: a discussion among regional stakeholders by Lek, D, Shrestha, M, Lhazeen, K, Tobgyel, T, Kandel, S, Dahal, G, Ghimire, YC, Shrestha, B, Ghimire, P, Hein, PS, Peto, TJ, Callery, JJ, Tripura, R, von Seidlein, L, Amaratunga, C, Lynch, CA, Dondorp, AM, Adhikari, B

“…While the vivax malaria burden remains challenging, the consistent decline in falciparum malaria in these countries over the last five years suggests that the goal is achievable. …”

Newborn screening for severe combined immunodeficiency in Malaysia: current status, challenges and progress by Chang, Wai Leng, Mohd Noh, Lokman, Abdul Latiff, Amir Hamzah, Woo, Kent Chee Keen, Ismail, Intan Hakimah, Abd Hamid, Intan Juliana, Siniah, Sangeetha, Zainal Abidin, Mohd Azri, Sham, Marina, Mat Ripen, Adiratna, Baharin, Mohd Farid, Abdul Wahab, Asrul, Zainudeen, Zarina Thasneem, Hashim, Ilie Fadzilah, Wong, Yee Ming, Ahmad Shawaludin, Mohamad Qazreen, Ali, Adli

“…Introduction: Early diagnosis of Severe Combined Immunodeficiency (SCID) increases survival outcomes and quality of life while significantly minimizing healthcare burden and costs. Despite growing evidence supporting the benefits and cost-effectiveness of SCID detection through newborn screening (NBS), it has yet to be implemented in Malaysia. …”
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Methodology for domain ontology development with human-centered design by Iqbal, Rizwan

“…Moreover, in existing literature, the notion of human centered design is neglected and there is a need to come up with methods which does not put burden on the audience for mastering them and should be easy to adapt for supporting ontology development. …”
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Data-driven brain emotional learning-based intelligent controller-PID control of MIMO systems based on a modified safe experimentation dynamics algorithm by Shahrizal, Saat, Mohd Ashraf, Ahmad, Mohd Riduwan, Ghazali

“…Furthermore, the low computational burden of MSEDA rendered it a strong alternative to heuristic multi-agent algorithms, which frequently encounter high computational costs with large controller design parameters.…”
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In vivo bone marrow microenvironment siRNA delivery using lipid–polymer nanoparticles for multiple myeloma therapy by Guimarães, Pedro PG, Figueroa-Espada, Christian G, Riley, Rachel S, Gong, Ningqiang, Xue, Lulu, Sewastianik, Tomasz, Dennis, Peter S, Loebel, Claudia, Chung, Amanda, Shepherd, Sarah J, Haley, Rebecca M, Hamilton, Alex G, El-Mayta, Rakan, Wang, Karin, Langer, Robert, Anderson, Daniel G, Carrasco, Ruben D, Mitchell, Michael J

“…Finally, we show that siRNA-based silencing of CyPA in a murine xenograft model of MM, either alone or in combination with the Food and Drug Administration (FDA)-approved MM therapeutic bortezomib, reduces tumor burden and extends survival. This nanoparticle platform may provide a broadly enabling technology to deliver nucleic acid therapeutics to other malignancies that home to bone marrow.…”
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A differential covariance matrix adaptation evolutionary algorithm for real parameter optimization by Ghosh, Saurav, Das, Swagatam, Roy, Subhrajit, Minhazul Islam, S. K., Suganthan, P. N.

“…Our comparative study indicates that although the hybridization scheme does not impose any serious burden on DCMA-EA in terms of number of Function Evaluations (FEs), DCMA-EA still enjoys a statistically superior performance over most of the tested benchmarks and especially over the multi-modal, rotated, and compositional ones in comparison to the other algorithms considered here.…”
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Validation of the Needs Assessment of Family Caregivers - cancer scale in an Asian population by Yang, Winson Fu Zun, Liu, Jianlin, Chan, Yiong Huak, Griva, Konstadina, Kuparasundram, Sangita, Mahendran, Rathi

“…Methods: Participants (n= 363) completed questions on sociodemographics, the Depression Anxiety Stress Scale,the Zarit Burden Interview, the Caregiver Quality of Life Index-Cancer scale, and the NAFC-C. …”
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Comparison of mental-physical comorbidity, risk of death and mortality among patients with mental disorders - a retrospective cohort study by Tan, Xiao Wei, Lee, Eng Sing, Toh, Matthias Paul Han Sim, Lum, Alvin Wai Mun, Seah, Darren Ee Jin, Leong, Khai Pang, Chan, Christopher Yi Wen, Fung, Daniel Shuen Sheng, Tor, Phern Chern

“…More attention and resources may be needed to tackle the burden of AUD.…”
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White-light-responsive prussian blue nanophotonic particles for effective eradication of bacteria and improved healing of infected cutaneous wounds by Chakraborty, Nayanika, Jha, Diksha, Singh, Vijay Pal, Kumar, Pradeep, Verma, Navin Kumar, Gautam, Hemant Kumar, Roy, Indrajit

“…The increasing burden of cutaneous wound infections with drug-resistant bacteria underlines the dire need for novel treatment approaches. …”
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Rule-based patient transition in an integrated healthcare system by Ng, Yan Leng.

“…This leads to an increased burden on the different levels of care settings thus the challenge having to deal with the diverse needs of different patients. …”
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A 15-year review of dengue hospitalizations in Singapore : reducing admissions without adverse consequences, 2003 to 2017 by Ang, Li Wei, Thein, Tun-Linn, Ng, Yixiang, Boudville, Irving Charles, Chia, Po Ying, Lee, Vernon Jian Ming, Leo, Yee-Sin

“…In the aftermath of the 2004–2005 dengue epidemic, hospitals refined their admission criteria for dengue cases to right-site dengue case management and reduce the burden of healthcare utilization and negative outcomes. …”
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Viral and immune dynamics of genital human papillomavirus infections in young women with high temporal resolution by Tessandier, N, Elie, B, Boué, V, Selinger, C, Rahmoun, M, Bernat, C, Grasset, S, Groc, S, Bedin, A, Beneteau, T, Bonneau, M, Graf, C, Jacobs, N, Kamiya, T, Kerioui, M, Lajoie, J, Melki, I, Prétet, J, Reyné, B, Schlecht-Louf, G, Sofonea, MT, Supplisson, O, Wymant, C, Foulongne, V

“…Human papillomavirus (HPV) infections drive one in 20 new cancer cases, exerting a particularly high burden on women. Most anogenital HPV infections are cleared in less than two years, but the underlying mechanisms that favour persistence in around 10% of women remain largely unknown. …”