Detecting changes in population trends in infection surveillance using community SARS-CoV-2 prevalence as an exemplar by Pritchard, E, Vihta, K-D, Eyre, DW, Hopkins, S, Peto, TEA, Matthews, PC, Stoesser, N, Studley, R, Rourke, E, Diamond, I, Pouwels, KB, Walker, AS, COVID-19 Infection Survey Team

Factors affecting duration of SARS-Cov-2 viral shedding in mildly symptomatic patients isolated in a community facility by Cheng, Hui Mei, Zhao, Xiahong, Lim, Wei Shyann, Tan, Beatrice Jia Min, Tey, Hong Liang

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Seroprevalence of SARS-CoV-2 in children and adolescents by Ratcliffe, H

“…The results showed a high prevalence of pre-existing immunity against seasonal coronaviruses when measuring IgG concentration of antibodies against spike protein but did not confer protection against SARS-CoV-2.</p> <br> <p>In serum, anti-nucleocapsid antibodies fell below the threshold of positivity more quickly than anti-spike protein receptor binding domain antibodies, suggesting community-based prevalence studies relying on these measures of infection may underestimate the burden of disease. …”

Chronic neuropsychiatric sequelae of SARS-CoV-2: protocol and methods from the Alzheimer's Association Global Consortium by de Erausquin, GA, Snyder, H, Brugha, TS, Newton, C

“…No available evidence supports the notion that cognitive impairment after SARS-CoV-2 infection is a form of dementia (ADRD or otherwise). …”

Self-organized canals enable long-range directed material transport in bacterial communities by Li, Ye, Liu, Shiqi, Zhang, Yingdan, Seng, Zi Jing, Xu, Haoran, Yang, Liang, Wu, Yilin

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Socioeconomic inequalities in risk of infection with SARS-CoV-2 delta and omicron variants in the UK, 2020-22: analysis of the longitudinal COVID-19 Infection Survey by Razieh, C, Shabnam, S, Dambha-Miller, H, Morris, EJA, Yates, T, Chudasama, Y, Zaccardi, F, Gillies, C, Banerjee, A, Pareek, M, Lacey, B, White, M, Khunti, K, Islam, N

“…</p> <p><strong>Setting</strong> COVID-19 Infection Survey, conducted by the Office for National Statistics and the University of Oxford, UK, a nationwide longitudinal survey to monitor SARS-CoV-2 infection in the community, 26 April 2020 to 31 January 2022.…”

Cost-utility analysis of molnupiravir plus usual care versus usual care alone as early treatment for community-based adults with COVID-19 and increased risk of adverse outcomes in... by Png, ME, Harris, V, Grabey, J, Hart, ND, Jani, BD, Butler, D, Carson-Stevens, A, Coates, M, Cureton, L, Dobson, M, Dorward, J, Evans, P, Francis, N, Gbinigie, OA, Hayward, G, Holmes, J, Hood, K, Khoo, S, Ahmed, H, Lown, M, McKenna, M, Mort, S, Nguyen-Van-Tam, J, Rahman, N, Richards, DB, Thomas, N, van Hecke, O, Hobbs, FR, Little, P, Yu, L-M, Butler, CC, Petrou, S

“…<p><strong>Background </p></strong>The cost-effectiveness of molnupiravir, an oral antiviral for early treatment of SARS-CoV-2, has not been established in vaccinated populations. …”

Vaccines: The Health of Nations - A Paradigm Shift by Datta, Shoumen

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From Sample to Answer: Innovations in sample processing and CRISPR-based diagnostics for enhanced clinical translation and field deployment by Arizti Sanz, Jon

“…However, the global diagnostic testing capacity is currently insufficient to effectively respond to emerging infectious disease threats, which has fueled the spread of Lassa, Ebola, SARS-CoV-2, and Zika virus in recent years. Globally, this diagnostic gap is particularly pronounced at the primary care or community level, an essential site for swift and effective response. …”
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Multicenter diagnostic evaluation of onsite COVID-19 Rapid Test (CTK Biotech) among symptomatic individuals in Brazil and the United Kingdom by Thompson, CR, Torres, PM, Kontogianni, K, Byrne, RL, LSTM Diagnostic group, Noguera, SV, Luna-Muschi, A, Marchi, AP, Andrade, PS, Dos Santos Barboza, A, Nishikawara, M, CONDOR steering group, Body, R, de Vos, M, Escadafal, C, Adams, E, Figueiredo Costa, S, Cubas-Atienzar, AI

“…To generate and to share accurate and independent data with the global community requires multisite prospective diagnostic evaluations of Ag-RDTs. …”

A multi-omics strategy to understand PASC through the RECOVER cohorts: a paradigm for a systems biology approach to the study of chronic conditions by Sun, J, Aikawa, M, Ashktorab, H, Beckmann, ND, Enger, ML, Espinosa, JM, Gai, X, Horne, BD, Keim, P, Lasky-Su, J, Letts, R, Maier, CL, Mandal, M, Nichols, L, Roan, NR, Russell, MW, Rutter, J, Saade, GR, Sharma, K, Shiau, S, Thibodeau, SN, Yang, S, Miele, L, NIH Researching COVID to Enhance Recovery (RECOVER) Consortium

“…Post-Acute Sequelae of SARS-CoV-2 infection (PASC or “Long COVID”), includes numerous chronic conditions associated with widespread morbidity and rising healthcare costs. …”

The IDentif.AI-x pandemic readiness platform: rapid prioritization of optimized COVID-19 combination therapy regimens by Blasiak, Agata, Truong, Anh T. L., Remus, Alexandria, Hooi, Lissa, Seah, Shirley Gek Kheng, Wang, Peter, Chye, De Hoe, Lim, Angeline Pei Chiew, Ng, Kim Tien, Teo, Swee Teng, Tan, Yee-Joo, Allen, David Michael, Chai, Louis Yi Ann, Chng, Wee Joo, Lin, Raymond T. P., Lye, David C., Wong, John Eu-Li, Tan, Gladys Gek-Yen, Chan, Conrad En Zuo, Chow, Edward Kai-Hua, Ho, Dean

“…IDentif.AI-x, a clinically actionable artificial intelligence platform, was used to rapidly pinpoint and prioritize optimal combination therapies against COVID-19 by pairing a prospective, experimental validation of multi-drug efficacy on a SARS-CoV-2 live virus and Vero E6 assay with a quadratic optimization workflow. …”
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