A conserved Mcm4 motif is required for Mcm2-7 double-hexamer formation and origin DNA unwinding by Champasa, Kanokwan, Blank, Caitlin, Friedman, Larry J, Gelles, Jeff, Bell, Stephen P

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Hypoxia-inducible factor cell non-autonomously regulates C. elegans stress responses and behavior via a nuclear receptor by Pender, Corinne Lenore, Horvitz, Howard Robert

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The Mitotic Exit Network integrates temporal and spatial signals by distributing regulation across multiple components by Zhou, Xiaoxue, Amon, Angelika B, Campbell, Ian Winsten.

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Interactions between a subset of substrate side chains and AAA+ motor pore loops determine grip during protein unfolding by Bell, Tristan Andrew, Baker, Tania, Sauer, Robert T

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Redox-dependent rearrangements of the NiFeS cluster of carbon monoxide dehydrogenase by Wittenborn, Elizabeth Charlot, Drennan, Catherine L

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Unsupervised discovery of temporal sequences in high-dimensional datasets, with applications to neuroscience by Mackevicius, Emily Lambert, Bahle, Andrew H, Williams, Alex H, Gu, Shijie, Denissenko, Natalia, Goldman, Mark S, Fee, Michale S.

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Molecular basis for catabolism of the abundant metabolite trans-4-hydroxy-L-proline by a microbial glycyl radical enzyme by Backman, Lindsey R., Huang, Yolanda Y, Andorfer, Mary, Gold, Brian, Raines, Ronald T, Balskus, Emily P, Drennan, Catherine L, Drennan, Catherine L

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Plasmodium Niemann-Pick type C1-related protein is a druggable target required for parasite membrane homeostasis by Istvan, Eva S, Das, Sudipta, Bhatnagar, Suyash, Beck, Josh R, Owen, Edward, Llinas, Manuel, Maddur Ganesan, Suresh, Niles, Jacquin, Winzeler, Elizabeth, Vaidya, Akhil B, Goldberg, Daniel E

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Across-species differences in pitch perception are consistent with differences in cochlear filtering by Walker, Kerry MM, Gonzalez, Ray, Kang, Joe Z, McDermott, Joshua Hartman, King, Andrew J

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Quantification of microenvironmental metabolites in murine cancers reveals determinants of tumor nutrient availability by Sullivan, Mark Robert, Danai, Laura V, Lewis, Caroline A, Chan, Sze Ham, Gui, Dan Yi, Kunchok, Tenzin, Dennstedt, Emily A, Vander Heiden, Matthew G., Muir, Alexander

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Comprehension of computer code relies primarily on domain-general executive brain regions by Ivanova, Anna A, Srikant, Shashank, Sueoka, Yotaro, Kean, Hope, Dhamala, Riva, O'Reilly, Una-May, Bers, Marina U, Fedorenko, Evelina G

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Whole-organism behavioral profiling reveals a role for dopamine in state-dependent motor program coupling in C. elegans by Cermak, Nathan, Yu, Stephanie K., Clark, Rebekah I., Huang, Yung-Chi, Baskoylu, Saba N, Flavell, Steven W, Flavell, Steven Willem

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Variation of connectivity across exemplar sensory and associative thalamocortical loops in the mouse by Mukherjee, Arghya, Bajwa, Navdeep, Lam, Norman H, Porrero, César, Clasca, Francisco, Halassa, Michael

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Identification of 1 distinct pH- and zeaxanthin-dependent quenching in LHCSR3 from chlamydomonas reinhardtii by Troiano, Julianne M., Moya, Raymundo, Schlau-Cohen, Gabriela S

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Framework for advancing rigorous research by Koroshetz, Walter J, Behrman, Shannon, Brame, Cynthia J, Branchaw, Janet L, Brown, Emery Neal, Clark, Erin A, Dockterman, David, Elm, Jordan J, Gay, Pamela L, Green, Katelyn M, Hsi, Sherry, Kaplitt, Michael G, Kolber, Benedict J, Kolodkin, Alex L, Lipscombe, Diane, MacLeod, Malcolm R, McKinney, Caleb C, Munafò, Marcus R, Oakley, Barbara, Olimpo, Jeffrey T, Percie du Sert, Nathalie, Raman, Indira M, Riley, Ceri, Shelton, Amy L, Uzzo, Stephen Miles, Crawford, Devon C, Silberberg, Shai D

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DDK regulates replication initiation by controlling the multiplicity of Cdc45-GINS binding to Mcm2-7 by De Jesús-Kim, Lorraine, Friedman, Larry J, Lõoke, Marko, Ramsoomair, Christian K, Gelles, Jeff, Bell, Stephen P

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A mobile genetic element increases bacterial host fitness by manipulating development by Jones, Joshua M, Grinberg, Ilana, Eldar, Avigdor, Grossman, Alan D

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ClpAP proteolysis does not require rotation of the ClpA unfoldase relative to ClpP by Kim, Sora, Zuromski, Kristin L, Bell, Tristan A, Sauer, Robert T, Baker, Tania A

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Phosphatidylinositol 3-phosphate and Hsp70 protect Plasmodium falciparum from heat-induced cell death by Lu, Kuan-Yi, Pasaje, Charisse Flerida A, Srivastava, Tamanna, Loiselle, David R, Niles, Jacquin C, Derbyshire, Emily

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Light-regulated allosteric switch enables temporal and subcellular control of enzyme activity by Shaaya, Mark, Fauser, Jordan, Zhurikhina, Anastasia, Conage-Pough, Jason E, Huyot, Vincent, Brennan, Martin, Flower, Cameron T, Matsche, Jacob, Khan, Shahzeb, Natarajan, Viswanathan, Rehman, Jalees, Kota, Pradeep, White, Forest M, Tsygankov, Denis, Karginov, Andrei V

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