Fabrication, Characterization and Biomedical Evaluation of a Statistically Optimized Gelatin Scaffold Enriched with Co-Drugs Loaded into Controlled-Release Silica Nanoparticles by Hina Younis, Hafeez Ullah Khan, Safirah Maheen, Malik Saadullah, Shahid Shah, Nabeel Ahmad, Sameer Alshehri, Mohammed Ali A. Majrashi, Abdullah Alsalhi, Rida Siddique, Mehwish Andleeb, Saleha Shabbir, Ghulam Abbas

“…Optimization of the MSNs-loaded scaffold was performed using central composite rotatable design (CCRD), where the effect of gelatin concentration (X1), plasticizer (X2) and freezing time (X3) on the entrapment of EN (Y1) and TA (Y2) and on the release of EN (Y3) and TA (Y4) from the scaffold were studied. …”
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Scenarios for future Indian HFC demand compared to the Kigali Amendment by Alex Hillbrand, Prima Madan, Manjeet Singh, Marie McNamara, Stephen O Andersen, Ajay Mathur, Rajendra Shende, Anjali Jaiswal

“…Results suggest that India’s annual HFC demand under current market trends could reach 76 MMT CO _2 -equivalent (CO _2 e) in 2030 and 197 MMT CO _2 e in 2050, from 23 MMT CO _2 e in 2020, making no changes to the current mix of HFCs in use. …”
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Von der klassischen Vorlesung zur Bologna-kompatiblen Lehrveranstaltung - Redesign einer Lehrveranstaltung by Christian Sengstag, Damian Miller

“…Vertikale Mobilität wurde weiter durch eine Sammlung von Videoaufnahmen früherer Vorlesungen ermöglicht, welche ebenfalls auf dem Web frei zugänglich sind. Mit dem Ziel, Vorwissen der Studierenden zu erheben und zu aktivieren, wurde eine Online-Umfrageapplikation sowie ein Wiki eingesetzt. …”
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Computer simulation based analysis of transient two-phase thermal evolutions during multiprobe cryosurgery of hepatic tissues embedded without or with blood vessels by Sorowar Hossain, S. M. Chapal Hossain, Mohammad Ferdows, Md. Zavid Iqbal Bangalee, Md. Shariful Alam

“…The simulation outcomes indicate that multiprobe cryosurgery is more effective to destroy the tumor tissue properly when the target tissue is located faraway from blood vessels. The simulation platform is anticipated to be valuable in optimizing pre-treatment plans of cryosurgery schemes while determining the number and position of cryoprobes in the neighborhood of blood vessels.…”
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Effect of low-density lipoproteins and trehalose on the quality of cryopreserved bovine semen by Elizabeth Varela-Giraldo, Alexandra Úsuga-Suárez, Juan E. Duque-Cortés, Jorge Gómez-Oquendo, Giovanni Restrepo-Betancur

“…Methods: Ten ejaculates from five bulls were cryopreserved under the treatments T1: pure egg yolk (PEY) at 20% v/v, T2: centrifuged egg yolk (CEY) at 20% v/v, T3: LDL at 8% v/v, T4: T at 100 mM, and T5: T at 100 mM plus LDL at 8% v/v (TLDL). …”
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Breakup process modeling and production of FeSiAl magnetic powders by close-coupled gas atomization by Pu Wang, Jiaqi Liu, Yannan Dong, Zhengqu Zhu, Jing Pang, Jiaquan Zhang

“…As the mass flow rate increased from 0.0050 to 0.0150 kg s−1, the gas to melt ratio decreased, but the d50 only increased from 32.3 to 40.7 μm, indicating that the mass flow rate of 0.0150 kg s−1 did not significantly affect the particle size distribution, but also contributed to improve the production efficiency and avoided the risk of the nozzle freeze-off. …”
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Importance of experimental information (metadata) for archived sequence data: case of specific gene bias due to lag time between sample harvest and RNA protection in RNA sequencing by Tomoko Matsuda

“…In the case of RNA sequencing (RNA-Seq), which reveals the presence and quantity of RNA in a biological sample at any moment, it is necessary to consider that gene expression responds over a short time interval (several seconds to a few minutes) in many organisms. Therefore, to isolate RNA that accurately reflects the transcriptome at the point of harvest, raw biological samples should be processed by freezing in liquid nitrogen, immersing in RNA stabilization reagent or lysing and homogenizing in RNA lysis buffer containing guanidine thiocyanate as soon as possible. …”
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Thawing process calculation of egg ingredients particles in minced meat by V. P. Agafonychev, V. N. Makhonina

“…Sausages from poultry meat are present on the domestic market. …”
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Efficient pathway for men fertility preservation in testicular cancer or lymphoma: a cross-sectional study of national 2018 data by Ségolène Prades, Sarah-Lyne Jos, Jacqueline Saïas-Magnan, Louis Bujan, Florence Eustache, Oxana Blagosklonov, Eric Lechevallier, Florence Brugnon, Vanessa Loup-Cabaniols, Dorian Bosquet, Marie Prades, Bérengère Ducrocq, Céline Chalas, Sandrine Giscard-d’Estaing, Anne Mayeur, Isabelle Koscinsky, Françoise Schmitt, Aline Papaxanthos-Roche, Marius Teletin, Emmanuelle Thibault, Damien Beauvillard, Sophie Mirallie, Béatrice Delepine, Annie Benhaim, Pascale May-Panloup, Ségolène Veau, Cynthia Frapsauce, Patricia Fauque, Régis Costello, Nathalie Rives, Catherine Metzler-Guillemain, Jeanne Perrin, the CECOS network

“…Abstract Background In 15–49 years-old men, the main cancers are testicular cancer (TC) and lymphomas (L): freezing of ejaculated sperm is primarily used for male fertility preservation (FP) before cancer treatment. …”
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A simple and robust nanosystem for photoacoustic imaging of bladder cancer based on α5β1-targeted gold nanorods by Massimo Alfano, Elisa Alchera, Angelina Sacchi, Alessandro Gori, Giacomo Quilici, Irene Locatelli, Chiara Venegoni, Roberta Lucianò, Anna Maria Gasparri, Barbara Colombo, Giulia Taiè, Jithin Jose, Paolo Armanetti, Luca Menichetti, Giovanna Musco, Andrea Salonia, Angelo Corti, Flavio Curnis

“…GNRs@PEG-Iso4 was stable and did not aggregate in urine or in 5% sodium chloride, or after freeze/thaw cycles or prolonged exposure to 55 °C, and, even more importantly, do not settle after instillation into the bladder. …”
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Study on the Properties of Multi-Walled Carbon Nanotubes (MWCNTs)/Polypropylene Fiber (PP Fiber) Cement-Based Materials by Xiangjie Niu, Yuanzhao Chen, Zhenxia Li, Tengteng Guo, Meng Ren, Yanyan Chen

“…The effects of multi-walled carbon nanotubes and polypropylene fiber on the durability of cement-based materials were studied using drying shrinkage tests and freeze–thaw cycle tests. …”
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The effect of decellularization protocols on characterizations of thermoresponsive and light-curable corneal extracellular matrix hydrogels by Ghasem Yazdanpanah, Elmira Jalilian, Xiang Shen, Khandaker N. Anwar, Yizhou Jiang, Sayena Jabbehdari, Mark I. Rosenblatt, Yayue Pan, Ali R. Djalilian

“…Abstract To compare the effects of two decellularization protocols on the characteristics of fabricated COrnea Matrix (COMatrix) hydrogels. Porcine corneas were decellularized with Detergent (De) or Freeze–Thaw (FT)-based protocols. …”
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Validation of Enzyme Immunoassay for Preclinical Pharmacokinetic Trials of Rituximab by V. V Pisarev, Maria M Ulyashova, Gelia N Gildeeva

“…The stability of the analyte in the rabbit blood serum was confirmed by storing samples for 6 hours at room temperature, for 50 days at —35 °C, and after 3 freeze-thaw cycles. The validated immunoassay was successfully used to determine the rituximab concentration in biological samples obtained in the rituximab pharmacokinetic trial in rabbits. …”
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Determination of barbiturates in hair samples by using a validated UHPLC-HRMS method: application in investigation of drug-facilitated sexual assault by Di Wen, Yan Shi, Xiaoguang Zhang, Bing Xie, Wenqiao Liu, Feng Yu, Ping Xiang, Bin Cong, Chunling Ma

“…Hair samples (black, approximate 25 cm long) were collected 3 months after the assault, and the proximal segments (0–5 cm from the root; each segment was 1 cm long) were analyzed. …”
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Validation of CloudSat-CPR Derived Precipitation Occurrence and Phase Estimates across Canada by Rithwik Kodamana, Christopher G. Fletcher

“…In this study, CloudSat-based precipitation occurrence and phase retrievals were validated at 26 stations across Canada maintained by Environment and Climate Change Canada (ECCC). …”
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Molecular Identification and Expression Analysis of an Intelectin Gene in the Yellow Catfish <i>Pelteobagrus fulvidraco</i> (Siluriformes: Bagridae) by Senhao Jiang, Yuting Lei, Yanxuan Li, Wanyan Sun, Ti Wang, Ruiting Ma, Qiuning Liu, Boping Tang

“…The full-length cDNA of <i>PfITLN</i> was 1132 bp, including a 5’-untranslated region (UTR) of 140 bp, a 3’-UTR of 110 bp, and an open reading frame (ORF) of 882 bp encoding a polypeptide of 293 amino acids, which contains a signal peptide and two fibrinogen-related domains (FReDs). …”
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Immunohistochemical visualization of lymphatic vessels in human dura mater: methodological perspectives by César Luis Vera Quesada, Shreyas Balachandra Rao, Reidun Torp, Per Kristian Eide

“…The dura specimens were prepared using three different methods: Paraformaldehyde (PFA) 4% (Method #1), paraformaldehyde (PFA) 0.5% (Method #2), and freeze-fixation (Method #3). …”
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Effects of alarm cues on behavior and physiology of the sea cucumber Apostichopus japonicus by Zihe Zhao, Xiang Li, Yingzhuo Sun, Xiyuan Huang, Jun Ding, Yaqing Chang, Chong Zhao

“…There was no significant difference in tentacle activity frequency (P = 0.705), indicating that alarm cues would not affect feeding behavior of sea cucumbers. In addition, there was also no significant difference in righting behavior of A. japonicus (P = 0.724), indicating that sea cucumbers probably respond to alarm cues through tube feet rather than tentacles or muscles. …”
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The faint young Sun problem revisited with a 3-D climate–carbon model &ndash; Part 1 by G. Le Hir, Y. Teitler, F. Fluteau, Y. Donnadieu, P. Philippot

“…One-dimensional radiative convective models (RCM) generally infer that high concentrations of greenhouse gases (CO₂, CH₄) are required to prevent the early Earth's surface temperature from dropping below the freezing point of liquid water and satisfying the faint young Sun paradox (FYSP, an Earth temperature at least as warm as today). …”
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Strawberries Improve Pain and Inflammation in Obese Adults with Radiographic Evidence of Knee Osteoarthritis by Jace Schell, R. Hal Scofield, James R. Barrett, Biji T. Kurien, Nancy Betts, Timothy J. Lyons, Yan Daniel Zhao, Arpita Basu

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