A new model for supraglacial hydrology evolution and drainage for the Greenland Ice Sheet (SHED v1.0) by P. Gantayat, A. F. Banwell, A. A. Leeson, A. A. Leeson, J. M. Lea, D. Petersen, N. Gourmelen, X. Fettweis

“…Understanding where, when, and how much meltwater is transferred to the bed is important because variability in meltwater supply to the bed can increase ice flow speeds, potentially impacting the hypsometry of the ice sheet in grounded sectors, and iceberg discharge to the ocean. Here we present a new, physically based, supraglacial hydrology model for the GrIS that is able to simulate (a) surface meltwater routing and SGL filling; (b) rapid meltwater drainage to the ice sheet bed via the hydrofracture of surface crevasses both in and outside of SGLs; (c) slow SGL drainage via overflow in supraglacial meltwater channels; and, by offline coupling with a second model, (d) the freezing and unfreezing of SGLs from autumn to spring. …”
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NEMO–ICB (v1.0): interactive icebergs in the NEMO ocean model globally configured at eddy-permitting resolution by R. Marsh, V. O. Ivchenko, N. Skliris, S. Alderson, G. R. Bigg, G. Madec, A. T. Blaker, Y. Aksenov, B. Sinha, A. C. Coward, J. Le Sommer, N. Merino, V. B. Zalesny

“…Substantial physical and dynamical responses to icebergs, throughout the global ocean, are explained by rapid propagation of density anomalies from high-to-low latitudes. Complementary to the baseline model used here, three prototype modifications to NEMO–ICB are also introduced and discussed.…”
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Soft ovarian stimulation protocol in polycystic ovary syndromes women inspired by gonadotropin stimulated intrauterine insemination cycles converted to rescue IVF: time to shift th... by Amina Nagy Elasy, Amany Mohamed Abedlghany

“…Secondary outcomes were the endocrinological profiles, gonadotropin dose, and duration of stimulation. …”
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Study of Formulation and Process Variables for Optimization of Piroxicam Nanosuspension Using 3² Factorial Design to Improve Solubility and In Vitro Bioavailability by Yahya Alhamhoom, Sandip M. Honmane, Umme Hani, Riyaz Ali M. Osmani, Geetha Kandasamy, Rajalakshimi Vasudevan, Sharanya Paramshetti, Ravindra R. Dudhal, Namrata K. Kengar, Manoj S. Charde

“…DSC and XRPD analysis of freeze-dried NS formulation showed conversion of PRX into a less crystalline form. …”
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QuEChERS-超高效液相色谱法测定食用油中5种抗氧化剂 by 李亚1，梁剑锋1，柯立坚2，钟水桥2，蒋德利2 LI Ya1, LIANG Jianfeng1,KE Lijian2, ZHONG Shuiqiao2,JIANG Deli2

“…The results showed that the linear relationship of the five antioxidants was good in the range of 1.0-100.0 mg/L, the detection limits were not more than 1.6 mg/kg, the spiked recovery rate was 85.78%-100.85%, and the RSD was 2.40%-6.01%. …”
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Dietary Supplementation with Fermented <i>Brassica rapa</i> L. Stimulates Defecation Accompanying Change in Colonic Bacterial Community Structure by Sachi Tanaka, Kana Yamamoto, Chisato Hamajima, Fuka Takahashi, Katsunori Endo, Yutaka Uyeno

“…To evaluate the detailed changes in the immune responses and the gut bacterial composition, assessed by high-throughput sequencing, we fed healthy mice with freeze-dried, fermented <i>B. rapa</i> L. for 2 weeks. …”
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RNA Extraction from Endoscopic Ultrasound-Acquired Tissue of Pancreatic Cancer Is Feasible and Allows Investigation of Molecular Features by Livia Archibugi, Veronica Ruta, Valentina Panzeri, Miriam Redegalli, Sabrina Gloria Giulia Testoni, Maria Chiara Petrone, Gemma Rossi, Massimo Falconi, Michele Reni, Claudio Doglioni, Claudio Sette, Paolo Giorgio Arcidiacono, Gabriele Capurso

“…PDAC cases underwent diagnostic EUS-TA, with needles being a 25G fine needle aspiration (FNA) in all patients and then either a 20G lateral core-trap fine needle biopsy (FNB) or a 25G Franseen FNB; the conservation methods were either snap freezing, RNALater or Trizol. …”
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Cryo-derived plants through embryogenesis showed same levels of vinblastine and vincristine (anticancer) in Catharanthus roseus and had normal genome size by A. Mujib, Samar Fatima, Moien Qadir Malik

“…Two osmotic agents (sugar and sorbitol) and three cryoprotective compounds, polyethylene glycol (PEG), dimethyl sulfoxide (DMSO) and glycerol were used at varying concentrations to protect cells from freezing damages. …”
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Folate-Modified Chitosan 5-Flourouraci Nanoparticles-Embedded Calcium Alginate Beads for Colon Targeted Delivery by Shafi Ullah, Asif Nawaz, Arshad Farid, Muhammad Shahid Latif, Muhammad Fareed, Shakira Ghazanfar, Charis M. Galanakis, Abdulhakeem S. Alamri, Majid Alhomrani, Syed Mohammed Basheeruddin Asdaq

“…Biodistribution studies also show that maximum drug amounts were found in the colon from nanoparticles-embedded beads. …”
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A low total motile sperm count in donor sperm obtained from commercial banks does not affect pregnancy rates from intrauterine insemination by Alyssa Hochberg, Michael H. Dahan, Trish Dinh, William Buckett, Jacob Ruiter-Ligeti

“…Chi-squared analyses and correlation coefficients were performed. Results: Overall, 9341 IUIs were conducted during the study period. …”
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Definition and impact of a quality index for radar-based reference measurements in the H-SAF precipitation product validation by A. Rinollo, G. Vulpiani, S. Puca, P. Pagliara, J. Kaňák, E. Lábó, L'. Okon, E. Roulin, P. Baguis, E. Cattani, S. Laviola, V. Levizzani

“…The precipitation field derived by radar data was compared with the PR-OBS-3 precipitation product, with varying thresholds of quality index: the impact of the introduction of the quality index defined on the statistical results of the satellite product validation as well as their sensitivity to the threshold choice were thus evaluated. Results show that PR-RMSE (a relative RMSE here introduced) is reduced from values between 2.5 and 3 to values around 1 when the quality threshold is increased from 0 (no threshold) to 0.8. …”
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Digitalität meets Inklusion: Vorstellung eines Selbstlernangebots für die Aus- und Fortbildung von Lehrkräften by Christoph Bierschwale, Michaela Vogt, Anna-Maria Kamin, Claudia Mertens, Saskia Bruns, Franziska Schaper, Katja Bremer

“…Bei der Konzeption der Selbstlerneinheit wurde auf eine möglichst zugängliche und lernförderliche Gestaltung sowie die Bereitstellung des Angebots als Open Educational Ressource (OER, freies Bildungsmaterial) geachtet. Der Beitrag beschreibt die grundlegenden methodisch-didaktischen Gestaltungsprinzipien, den Aufbau und den Inhalt des Selbstlernkurses und diskutiert vor diesem Hintergrund Potenziale und Herausforderungen eines solchen Angebots.   …”
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Role of Frozen Sections in Diagnosing Female Genital Tract Lesions: A Tertiary Centre Study in Chennai, India by M Ranjani, Sathish Selvakumar, S Dinesh Kumar, Maya Menon, K Meenakshisundaram

“…Artefacts like poor morphology due to tissue freezing, nucleomegaly, poor sectioning and section folding were observed in the discordant cases. …”
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Characterization of Green and Yellow Papaya (<i>Carica papaya</i>) for Anti-Diabetic Activity in Liver and Myoblast Cells and Wound-Healing Activity in Fibroblast Cells by Haiwen Li, Obaid Ullah Beg, Ahmed Reza Rafie, Sadia Kanwal, Alexandra Ovalle-Cisneros, Milton Omar Faison, Rafat Ali Siddiqui

“…Leaves, skin, pulp, and seed samples from papayas were freeze-dried and then extracted in water or 80% methanol. …”
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The earlier the initiation of gonadotropin in poor responders in luteal phase stimulation protocols, the better by Jia Huang, Jia Huang, Luxin Liu, Luxin Liu, Yue Wu, Yue Wu, Benyu Miao, Benyu Miao, Yubin Li, Yubin Li, Canquan Zhou, Canquan Zhou, Yanwen Xu, Yanwen Xu

“…A total of 327 poor responders fulfilling Bologna criteria underwent LPS with IVF/ICSI treatment. HMG and letrozole were administrated after ovulation. Patients were stratified into three groups according to the gonadotropin start day: early, early-mid, and mid-late luteal phase. …”
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Evaluation of elder (Sambucus nigra) varieties and candidates for the canning industry. Results of the composition studies by M. Stéger-Máté, E. Horváth, J. Barta

“…After having obtained a juice, a concentrate from the species has been made and — after freezing — the aquesoluble dry substance and the acid content, as well as the colour parameters were monitored. …”
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Efficacy and evaluation of therapeutic exercises on adults with Parkinson’s disease: a systematic review and network meta-analysis by Yong Yang, Guotuan Wang, Shikun Zhang, Huan Wang, Wensheng Zhou, Feifei Ren, Huimin Liang, Dongdong Wu, Xinying Ji, Makoto Hashimoto, Jianshe Wei

“…For concern of falling, five types of exercise were more effective than CON. …”
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NO SAFETY CONCERNS OBSERVED WHEN THE ADJUVANTED RECOMBINANT ZOSTER VACCINE (RZV) AND THE COVID-19 MRNA-1273 BOOSTER WERE CO-ADMINISTERED IN ≥50-YEAR-OLDS by A. Naficy, P. Pirrotta, A. Kuxhausen, J. Miller, B. Leav, A. Mwakingwe-Omari

“…In each group, most solicited AEs were mild/moderate in intensity and each with ≤2.5 days median duration, the most frequent were injection site pain, myalgia, and fatigue. …”
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Trends in the indices of precipitation phases under current warming in Poland, 1966–2020 by Ewa B. ŁUPIKASZA, Łukasz MAŁARZEWSKI

“…The strongest and widespread were increasing trends in rains (+1.74 for LqNd, +5.35 mm for LqT, +3.51% for LqNd%, +4.08% for LqT% per decade) and decreasing trends in snowfalls (−1.92 for SdNd, −3.12 mm for SdT, −3.65% for SdNd%, −3.26% for SdT% per decade) in winter when the warming was weakest but average temperature was close to freezing point. …”
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Potential modification of the UKPDS risk engine and evaluation of macrovascular event rates in controlled clinical trials by Yang F, Ye J, Pomerantz K, Stewart M

“…Methods: Data sources were summary demographic and risk factor data from the major type 2 diabetes mellitus outcomes studies, including ACCORD, ADVANCE, VADT, RECORD, PROactive, ADOPT, and BARI 2D. …”
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