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The metal ion-dependent adhesion site motif of the Enterococcus faecalis EbpA pilin mediates pilus function in catheter-associated urinary tract infection
Published 2014“…However, the endocarditis- and biofilm-associated pilus (Ebp), a member of the sortase-assembled pilus family, was shown to play a role in a mouse model of E. faecalis ascending UTI. The Ebp pilus comprises the major EbpC shaft subunit and the EbpA and EbpB minor subunits. …”
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Journal Article -
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Filamentous oligomer structure reconstruction and a new filament picking method for Cryo-EM micrographs
Published 2022“…Facilitated by NAIP5 and activates downstream ASC-CASP1 inflammasome signaling axis, the CARD domain in NLRC4 relays the activation signal via a cooperative oligomerization process. …”
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Thesis-Doctor of Philosophy