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Cardiovascular magnetic resonance before invasive coronary angiography in suspected non-ST-segment elevation myocardial infarction
Published 2024“…</p> <br> <p><strong>Results:</strong> Early CMR (median 33 hours postadmission and 4 hours pre-ICA) confirmed only 52% (52 of 100) of patients had subendocardial infarction, 15% transmural infarction, 18% nonischemic pathologies (myocarditis, takotsubo, and other forms of cardiomyopathies), and 11% normal CMR; 4% were nondiagnostic. Subanalyses according to ICA findings showed that, in patients with obstructive coronary artery disease (73 of 100), CMR confirmed only 84% (61 of 73) had MI, 10% (7 of 73) nonischemic pathologies, and 5% (4 of 73) normal. …”
Journal article -
2
The effect of temperature on permittivity measurements of aqueous solutions of glucose for the development of non-invasive glucose sensors based on electromagnetic waves
Published 2023“…The rise in thermal energy normally causes dipolar liquids like water to vibrate and rotate disrupting the alignment of the dipoles in response to an electric field thereby reducing its permittivity. …”
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3
An induced population of Trypanosoma cruzi epimastigotes more resistant to complement lysis promotes a phenotype with greater differentiation, invasiveness, and release of extracel...
Published 2022“…Here, we have selected a population of epimastigotes (a replicative form) from through two rounds of exposure to normal human serum (NHS), to reach 30% survival (2R population). …”
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Role of N-WASP in cell proliferation : implication for organ development and cancer
Published 2020“…Moreover, N-WASP KO mammary glands also displayed significantly higher collagen content around the mammary ducts suggesting reduced invasion these ducts. In-vitro experiments with N-WASP knockdown, normal mammary epithelial cell line, MCF10A (MCF10AKD) also showed reduced proliferation, migration, invasion and cell-cell adhesion. …”
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Thesis-Doctor of Philosophy -
5
Cervicitis decidualis mimicking cervical cancer in pregnancy
Published 2024“…Whilst magnetic resonance imaging (MRI) supported a diagnosis of cervical cancer, cervical tissue biopsies showed decidual reaction and no invasion. Cervical appearance postpartum reverted back to normal. …”
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Low magnetic field exposure alters prostate cancer cell properties
Published 2024“…The 4 h LMF exposure caused a significant increase in MMP2 and MMP9, as well as in onco-miRs miR-155, miR-210, miR-21, but a significant reduction in tumour-suppressor miRs (miR-200c and miR-126) in the metastatic PC3 cells, compared with normal PNT2 cells. In addition, 4 h LMF exposure significantly induced cellular invasion of PC3 cells. …”
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IGF-1R expression is associated with HPV-negative status and adverse survival in head and neck squamous cell cancer
Published 2015“…IGF-1R was detected in the cell membrane of 36% and cytoplasm of 92% of HNSCCs; in 64 cases with matched normal tonsillar epithelium, IGF-1R was overexpressed in the HNSCCs (P < 0.001). …”
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Investigation of fluorescence lifetime imaging for quantitative cervical cancer screening and diagnosis
Published 2015“…Categories comprising normal, cervical intraepithelial neoplasia (CIN1, CIN2, CIN3), squamous cell carcinoma (SCC) and microinvasive were imaged and analyzed. …”
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Thesis -
9
Physics-informed neural network for fast prediction of temperature distributions in cancerous breasts as a potential efficient portable AI-based diagnostic tool
Published 2024“…The proposed PINN method combines deep learning and physical principles to predict the temperature distributions in breast tissues and identify potential abnormal regions indicating the presence of tumors. The PINN model is normally trained by physics in terms of the residuals of the heat transfer equation, as well as boundary conditions with and without datasets of surface thermal imaging data concerning cancerous breast tissues, which can be used for future inverse thermal modeling to calculate tumor sizes and locations. …”
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Journal Article -
10
Effect of heat-producing needling technique on the local skin temperature : clinical dataset
Published 2020“…A total of 30 healthy participants received four successive sessions of heat-producing acupuncture treatment, non-acupoint heat-producing acupuncture treatment, normal stable acupuncture treatment, and non-invasive sham acupuncture treatment at the ST36 acupoint in a random sequence. …”
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Journal Article -
11
Know Thy Cell-Free DNA: Early Detection of Microsatellite Instability Using Ultra-Low-Pass Cell-Free DNA Sequences
Published 2024“…Microsatellites are inherently more mutable than other genomic locations, and since cancer cells undergo many more cell divisions, microsatellites are useful for distinguishing tumor DNA from normal (non-cancerous) DNA. Microsatellite instability (MSI) arises as a result of mismatch repair deficiency (MMRD), wherein a patient loses function of both copies of certain genes related to mismatch repair. …”
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Thesis -
12
Mapping the Unseen: In Vivo CEST-MRI of Creatine Reveals Improved Cardiac Energetics in Subjects with Obesity Following Bariatric Surgery
Published 2023“…Subjects with obesity had significantly lower CEST contrast compared to subjects with normal BMI (n = 10), but this contrast was normalized after the surgery, and statistically similar to non-obese cohort, indicating an improvement in myocardial energetics. …”
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The role of fibroblasts in cancer progression, therapy resistance and field cancerization
Published 2017“…Given our observations that CAFs augment oxidative stress within the tumor microenvironment, we investigated whether the readily diffusible ROS, H2O2, could promote oncogenic transformation of adjacent normal epithelia and stromal fibroblasts. Indeed, epithelial cells at various stages of oncogenic transformation exhibited a differential response to H2O2 in terms of proliferation and invasiveness. …”
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Thesis -
14
Tsewang Norbu NGB
Published 2025“…("in the Tibetan language"), normally follows the Sanskrit title. Rarely, there may be further titles, representing what are understood to be transcriptions of titles in other non-Tibetan languages. …”
Dataset -
15
Time frequency analysis of functional MR images
Published 2014“…This new perspective uses temporal autocorrelation values instead of the normally used low-frequency amplitude and seed-region time-series. …”
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Thesis -
16
Quantitative analysis of coronary artery from computed tomography angiography images
Published 2016“…Most commonly, diameter stenosis is measured because of the popularity of projection-based invasive angiography, which is measured as the ratio of the reduction in vessel diameter to the proximal normal diameter [4]. …”
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Thesis -
17
Physical unclonable function based solutions to unification of user, device and data authentication
Published 2020“…Experimental results show that the DVS sensor meets the quality criteria in PUF operation without compromising its normal imaging performance.…”
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Thesis-Doctor of Philosophy -
18
Investigations into high resolution imaging and contouring for diagnostic bio-applications
Published 2016“…Research is in progress around the world for finding methods which are minimally invasive and which can provide accurate results with minimum patient discomfort. …”
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Thesis