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AMIC Seminar on Television Development in the Asia-Pacific Region : Jakarta, Dec 8-9, 1994 : [welcome address]
Published 2008Get full text
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Conference Paper -
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NIR “matchbox size” spectrometer can quantify and detect malaria infection in Plasmodium falciparum infected red blood cells
Published 2020“…New point-of-care diagnostic approaches for malaria that are highly sensitive, portable and affordable are urgently needed to meet the World Health Organization’s objective of reducing malaria cases and related life losses by at least 90% globally on or before 2030.1 In this study, an ultra-cheap matchbox size near-infrared (NIR) spectrophotometer was used for the first time to detect and quantify malaria infection in vitro from isolated dried red blood cells using a fingerpick volume (15 μl) of blood, down to 0.0001% parasitemia.…”
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Conference Paper -
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Infections diagnosed in children and young people screened for malaria in UK emergency departments: a retrospective multi-centre study
Published 2024“…</p> <br> <p><strong>Aims:</strong> To describe imported infections in CYP arriving from malaria-endemic areas and presenting to UK emergency departments (ED) who were screened for malaria.…”
Journal article -
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Neutralizing antibodies against plasmodium falciparum associated with successful cure after drug therapy
Published 2018Subjects: Get full text
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Journal Article -
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Evaluation of the precision of the Plasmodium knowlesi growth inhibition assay for Plasmodium vivax Duffy-binding protein-based malaria vaccine development
Published 2024“…Recent data indicate increasing disease burden and importance of Plasmodium vivax (Pv) malaria. A robust assay will be essential for blood-stage Pv vaccine development. …”
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Whole-cell phenotypic screening of Medicines for Malaria Venture Pathogen Box identifies specific inhibitors of Plasmodium falciparum late-stage development and egress
Published 2020“…We report a systematic, cellular phenotype-based antimalarial screening of the Medicines for Malaria Venture Pathogen Box collection, which facilitated the identification of specific blockers of late-stage intraerythrocytic development of Plasmodium falciparum First, from standard growth inhibition assays, we identified 173 molecules with antimalarial activity (50% effective concentration [EC50] ≤ 10 μM), which included 62 additional molecules over previously known antimalarial candidates from the Pathogen Box. …”
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Journal Article -
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Cell-free hemoglobin mediated oxidative stress is associated with acute kidney injury and renal replacement therapy in severe falciparum malaria: an observational study
Published 2017“…Background: Intravascular hemolysis is an intrinsic feature of severe malaria pathophysiology but the pathogenic role of cell-free hemoglobin-mediated oxidative stress in severe malaria associated acute kidney injury (AKI) is unknown. …”
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Journal Article -
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Chloroquine has shown high therapeutic efficacy against uncomplicated Plasmodium vivax malaria in southern Ethiopia: seven decades after its introduction
Published 2024“…<p><strong>Background: </strong><em>Plasmodium vivax</em> malaria is a leading cause of morbidity in Ethiopia. …”
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Cost of the national malaria control program and cost-effectiveness of indoor residual spraying and insecticide-treated bed net interventions in two districts of Madagascar
Published 2024“…Background: Madagascar has made significant progress in the fight against malaria. However, the number of malaria cases yearly increased since 2012. …”
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Gametocyte carriage in uncomplicated plasmodium falciparum malaria following treatment with artemisinin combination therapy: a systematic review and meta-analysis of individual patient data
Published 2016“…<p><strong>Background</strong></p> <p>Gametocytes are responsible for transmission of malaria from human to mosquito. Artemisinin combination therapy (ACT) reduces post-treatment gametocyte carriage, dependent upon host, parasite and pharmacodynamic factors. …”
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Analyses of human vaccine-specific circulating and bone marrow-resident B cell populations reveal benefit of delayed vaccine booster dosing with blood-stage malaria antigens
Published 2024“…We have previously reported primary endpoints of a clinical trial testing two vaccine platforms for the delivery of Plasmodium vivax malaria DBPRII: viral vectors (ChAd63, MVA), and protein/adjuvant (PvDBPII with 50µg Matrix-M™ adjuvant). …”
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A mixed methods study investigating factors affecting adherence to Plasmodium vivax malaria primaquine radical cure regimens among migrants along the Myanmar-Thailand border
Published 2025“…Background: The countries within the Greater Mekong Region of Southeast Asia have pledged to eliminate malaria by 2030. Elimination of Plasmodium vivax malaria is challenging as it requires radical cure to prevent relapse. …”
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NAPE-PLD, a viable antimalarial drug target?
Published 2024Subjects: Get full text
Final Year Project (FYP) -
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Blood-stage malaria vaccine candidate RH5.1/Matrix-M in healthy Tanzanian adults and children; an open-label, non-randomised, first-in-human, single-centre, phase 1b trial
Published 2024“…<p><strong>Background:</strong> A blood-stage Plasmodium falciparum malaria vaccine would provide a second line of defence to complement partially effective or waning immunity conferred by the approved pre-erythrocytic vaccines. …”
Journal article