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    Fasting-induced torpor in mice: effects on sleep and behaviour by Wilcox, SL

    Published 2023
    “…Overall, this thesis provides novel insights into the characteristics, neurophysiology, and regulation of fasting-induced torpor in mice. Moreover, the data presented here highlight the potential for torpor to be a potential confound in research using fasting techniques if not adequately controlled for.…”
    Thesis
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    Multiplexed CRISPR/CAS9‐mediated engineering of pre‐clinical mouse models bearing native human B cell receptors by Wang, Xuesong, Ray, Rashmi, Kratochvil, Sven, Melzi, Eleonora, Lin, Ying‐Cing, Giguere, Sophie, Xu, Liling, Warner, John, Cheon, Diane, Liguori, Alessia, Groschel, Bettina, Phelps, Nicole

    Published 2024
    “…Here we report a one‐step CRISPR/Cas9 KI methodology to combine the insertion of human germline immunoglobulin heavy and light chains at their endogenous loci in mice. We validate this technology with the rapid generation of three BCR KI lines expressing native human precursors, instead of computationally inferred germline sequences, to HIV broadly neutralizing antibodies. …”
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    Article
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