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81
The impact of death and dying on the personhood of medical students : a systematic scoping review
Published 2021“…The Split Approach revealed similar themes and categories that correspond to the Innate, Individual, Relational and Societal domains in the Ring Theory of Personhood. …”
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Journal Article -
82
Effects of thrombin and its related peptide fragments on neutrophils
Published 2018“…In addition, these peptides were shown to have immunomodulatory effects on monocytes, but whether they have any effects on the other major innate immune cells, neutrophils, was not known. Hence, we aimed to address the immunomodulatory potential of these C-terminal truncations on neutrophil functions. …”
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Thesis -
83
Changes in cerebrospinal fluid balance of TNF and TNF receptors in naïve multiple sclerosis patients : early involvement in compartmentalised intrathecal inflammation
Published 2021“…Combined correlation and pathway analysis (ingenuity) of the CSF protein pattern associated with TNF expression (encompassing elevated levels of BAFF, IFN-γ, IL-1β, IL-10, IL-8, IL-16, CCL21, haptoglobin and fibrinogen) showed a particular relationship to the interaction between innate and adaptive immune response. The CSF sTNF-R1-associated pattern (encompassing high levels of CXCL13, TWEAK, LIGHT, IL-35, osteopontin, pentraxin-3, sCD163 and chitinase-3-L1) was mainly related to altered T cell and B cell signalling. …”
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Journal Article -
84
Structural and biochemical mechanisms of NLRP1 inhibition by DPP9
Published 2022“…Nucleotide-binding domain, leucine-rich repeat receptors (NLRs) mediate innate immunity by forming inflammasomes. Activation of the NLR protein NLRP1 requires autocleavage within its function-to-find domain (FIIND)1-7. …”
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85
Conservation of red blood cell signalling in Plasmodium merozoite invasion
Published 2023“…It is though clear that the parasite has exploited innate RBC signalling cascades to direct invasion. …”
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Thesis-Doctor of Philosophy -
86
Aqueous-only exfoliation of pristine graphite to graphene : towards sustainable, multifunctional polymer nanocomposites
Published 2019“…In addition to being the polymer matrix and stabilizer, WPU endowed the sensors with shape conformality too, which significantly increased the real-life sensitivity of the sensors in monitoring biomechanical deformations and reproducing blood-pressure waveforms. This innate shape-conformality obviated the need for an additional skin-conformal layer. …”
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Thesis -
87
Self-healing materials for flexible electronic devices
Published 2020“…However, they still suffer from innate problems like mechanical rupture, scratching and bending torsion because of their “soft” and flexible nature related to their solid counterparts. …”
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Thesis-Doctor of Philosophy -
88
Part I : Peptide functionalized materials for gram-negative bacteria targeted PDT and LPS sensing. Part II : Small peptide and membrane lipid based self-assembled nanostructures fo...
Published 2014“…Generally, Gram-negative bacterial pathogens have additional outer membranes mainly composed of highly conserved and unique lipopolysaccharide (LPS) molecules, which serve as permeability barriers to prevent the cell bodies from toxic antimicrobial molecules1-2 including many photosensitizers, which have been successfully used in photoinactivation of Gram-positive strains.3-4 Furthermore, LPS, a potent inducer to human innate immune systems, hence called endotoxin, is now primarily responsible for sepsis associated with the infections of Gram-negative pethogens.5-6 Therefore, the most promising strategy is use of LPS neutralizing peptide as the binding ligand to deliver antibacterial agents meanwhile minimize the side effects.7 The first objective of the research in part I is the design and synthesis of photosensitizer-peptide conjugates for multivalent targeted cellular imaging and photodynamic inactivation (PDI) against Gram-negative bacterial strains. …”
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Thesis -
89
Computational analysis for infectious diseases surveillance and host-pathogen interactions (in the context of Influenza A viruses)
Published 2017“…TRIM21, TRIM26, IRF2, and SAMHD1) might support the replication of IAV through suppression of the innate and adaptive antiviral immune responses. The other up-regulated IHFs could also enhance the replication of IAV at different stages of the virus lifecycle: endocytosis (BTC), prevention of apoptosis (TIMM17A), nuclear import (JAK2), and translation elongation of viral proteins (HEXIM1). …”
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Thesis-Doctor of Philosophy -
90
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91
Swimming in Data
Published 2024“…To compete in the Olympics is to have arrived at the pinnacle of one’s sport. It is the realization of a dream shared by the youngest summer league swimmer and the most outstanding professional. …”
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92
Swallow me (Again)
Published 2024“…The artwork presents a speculative emancipation ritual questioning the ideology of healing and its possibility in the context of something so innately present. Perhaps the only way to end a cycle of trauma is to remove its latest vessel from the world.…”
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Final Year Project (FYP) -
93
Force Dynamics of the Rat Lateral Gastrocnemius Muscle after Undergoing Sensory Protection
Published 2024“…Key FVP parameters such as peak velocity and specific peak power exhibited higher percent differences for the Sensory Protected muscles, but lower percent differences in pennation angles and physiological cross-sectional area, suggesting that sensory reinnervation may influence muscle structure and fundamental force dynamics. …”
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Thesis -
94
Injectable and biomimetic poly (ethylene glycol) hydrogel systems for in situ therapeutic cell delivery
Published 2017“…Elastin has been conjugated into gelatin-PEG hydrogel to innately guide cell behavior and help the remolding of new ECM in 3-D microenvironment for better mimicking natural ECM. …”
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95
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96
Advanced detection for blu-ray disc optical recording
Published 2010“…Therefore, the fate of the fourth generation optical recording system may innately lie on a breakthrough in a genre of Constrained Codes superior to that of the (1,7) Code.…”
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Final Year Project (FYP) -
97
Novel nanogel formulations with good antibacterial activities against wound infections
Published 2024“…This paper introduces a novel nanogel formulation for antibacterial purposes on wound dressings, specifically targeting MRSA bacteria. The formulation is innately antibacterial with oligoimidazolium (OIM) and alginate as its crosslinking agents and loaded with NAC. …”
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Final Year Project (FYP) -
98
Inclusion of cross-linked elastin in gelatin/PEG hydrogels favourably influences fibroblast phenotype
Published 2021“…The capacity of a biomaterial to innately modulate cell behavior while meeting the mechanical property requirements of the implant is a much sought-after goal within bioengineering. …”
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Journal Article -
99
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A neural clock underlying the temporal dynamics of an auditory memory
Published 2024“…This activity was present as early as the very first day of tutoring, perhaps indicating that HVC connectivity is innately predisposed to produce sparse sequential representations of song. …”
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Thesis