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Optogenetic release of ACh induces rhythmic bursts of perisomatic IPSCs in hippocampus.
Published 2011-01-01“…L-IPSC occurred more reliably in slices treated with eserine and a very low concentration of 4-AP, which were therefore used in most experiments. The rhythmic, L-IPSCs were driven primarily by muscarinic ACh receptors (mAChRs), and could be suppressed by endocannabinoid release from pyramidal cells. …”
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Genetic control of a central pattern generator: rhythmic oromotor movement in mice is controlled by a major locus near Atp1a2.
Published 2012-01-01“…Fluid licking in mice is a rhythmic behavior that is controlled by a central pattern generator (CPG) located in a complex of brainstem nuclei. …”
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Abnormal theta and alpha oscillations in children and adolescents with first-episode psychosis and clinical high-risk psychosis
Published 2024-03-01“…However, as previous studies have focused on adults with psychosis, it is unclear whether neurobiological impairments in cognitive control are present in children and adolescents with first-episode psychosis (FEP) or clinical high-risk (CHR) state for psychosis. Aims To explore the deficits of electroencephalogram related to cognitive control tasks in children and adolescents with FEP and CHR. …”
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Using optical stimulation to study the developing thalamocortical circuit in mouse somatosensory cortex
Published 2014“…These transient pathways could collaborate to regulate early rhythmic patterns of activity in L4 that are fundamental for maturation of thalamocortical pathways.…”
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Local Optogenetic Induction of Fast (20-40 Hz) Pyramidal-Interneuron Network Oscillations in the In Vitro and In Vivo CA1 Hippocampus: Modulation by CRF and Enforcement of Perirhin...
Published 2016-04-01“…Here, using selective Channelrhodopsin-2 (ChR2) expression in mouse forebrain glutamatergic cells, we were able to locally, temporally precisely, and reliably induce fast (20-40 Hz) field potential oscillations in hippocampal area CA1 in vitro (at 25°C) and in vivo (i.e., slightly anaesthetized NEX-Cre-ChR2 mice). …”
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Enhancing motor cortical theta and gamma oscillations using closed-loop phase-dependent optogenetic stimulation
Published 2024“…To achieve this, motor cortical LFPs were recorded in PV-Cre and RBP4-Cre (retinol-binding-protein-4) mice, in which these neurons were transfected with Channelrhodopsin-2 (ChR2). Using our recently developed phase-tracking system (OscillTrack), blue-light pulses were delivered at four phases of the ongoing motor cortical theta oscillation in awake, head-fixed mice. …”
Thesis