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Characterizing the function of the Arl15 gene and its role in the development of metabolic traits
Published 2019“…The aim of this thesis was to test the Arl15 gene as a functional candidate for metabolic traits.…”
Thesis -
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Use of static overpressure to assess the role of acoustic cavitation in ultrasound-mediated gene transfection
Published 2022Journal article -
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Role of Interferon-stimulated gene 15 (ISG15) in replication fork progression and PARP inhibitor resistance in cancer
Published 2024“…Understanding PARP (Poly-ADP ribose polymerase) inhibitor resistance is crucial in cancer therapy, particularly in treating cancers associated with BRCA mutations. The role of ISG15 (Interferon-Stimulated Gene 15) in PARP inhibitor resistance adds a layer of complexity to this phenomenon. …”
Thesis -
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Parenting by lying and children’s lying to parents: the moderating role of children’s beliefs
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Working Paper -
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Role of substrate rigidity on cell migration
Published 2017“…Further examination of focal adhesion protein levels, paxillin and vinculin, by Western Blot revealed inconclusive results. Hence, further studies are required to characterize the role of matrix rigidity in regulating formation of focal adhesions and cellular migration.…”
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Final Year Project (FYP) -
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Integrins : their roles as mechanosensors and as targets in therapeutics.
Published 2012Get full text
Final Year Project (FYP) -
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The role of bidirectional nucleocytoplasmic transport in apoptosis
Published 2012Get full text
Thesis -
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The role of polarity in nonplanar semiconductor nanostructures
Published 2020Get full text
Journal Article -
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The role played by Singlish in the lives of migrants in Singapore
Published 2015“…To ease such tensions, integration is essential and this thesis investigates the role of Singlish, its usage and function in particular, in the lives of migrants in Singapore. …”
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Final Year Project (FYP) -
12
Role of different dendritic cell subsets in vivo
Published 2015“…In a dextran sodium sulphate (DSS) model of colonic inflammation, ablation of CD103+ CD11b- colonic DCs resulted in exacerbated colitis, while ablation of colonic CD103+ CD11b+ DCs resulted in resistance to colitis when subjected to the same DSS regiment. Hence our results highlight the opposing roles of these two distinct colonic DC subsets in controlling DSS-induced colonic inflammation. …”
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Thesis -
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The role of EZH2-VAV interaction in tumorigenesis
Published 2015“…Polycomb group protein EZH2 is a histone methyltransferase that modifies chromatin structure to alter gene expression during various important biological and pathogenic processes. …”
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Thesis -
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Role of polyamines in biofilm - based water decontamination
Published 2015Get full text
Final Year Project (FYP) -
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Understanding the role of Enterococcus faecalis in polymicrobial wounds
Published 2023“…In addition, using a library of isogenic E. faecalis transposon mutants, I identified genes within E. faecalis Type VII secretion system (T7SS) gene locus involved in the contact-dependent antagonism of S. aureus. …”
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Thesis-Doctor of Philosophy -
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The role of mainstreamness and interdisciplinarity for the relevance of scientific papers
Published 2021Get full text
Journal Article -
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The role of POPX2 in the regulation of hippo pathway
Published 2018“…The Hippo pathway has gained immense attention due to its key role in regulating organ size as well as its relevance to tissue regeneration and cancer. …”
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Thesis -
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An essential role for maternal control of Nodal signaling
Published 2013Get full text
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Journal Article -
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The role of SPRTN protease in colorectal cancer chemotherapy
Published 2023“…In order to address this need, the role of SPRTN in colorectal cancer chemotherapy is investigated for the first time in this thesis.…”
Thesis