Dynamic altruistic cooperation within breast tumors by Muhammad Sufyan Bin Masroni, Lee, Kee Wah, Lee, Victor Kwan Min, Ng, Siok Bian, Law, Chao Teng, Poon, Kok Siong, Lee, Bernett Teck Kwong, Liu, Zhehao, Tan, Yuen Peng, Chng, Wee Ling, Tucker, Steven, Ngo, Lynette Su-Mien, Yip, George Wai Cheong, Nga, Min En, Hue, Susan Swee Shan, Putti, Thomas Choudary, Bay, Boon Huat, Lin, Qingsong, Zhou, Lihan, Hartman, Mikael, Loh, Tze Ping, Lakshmanan, Manikandan, Lee, Sook Yee, Tergaonkar, Vinay, Chua, Huiwen, Lee, Adeline Voon Hui, Yeo, Eric Yew Meng, Li, Mo-Huang, Chang, Chan Fong, Kee, Zizheng, Tan, Karen Mei-Ling, Tan, Soo Yong, Koay, Evelyn Siew-Chuan, Archetti, Marco, Leong, Sai Mun

Get full text

Macrophage-matrix interactions in the breast tumour microenvironment: the case of tenascin-C by Gammage, A

“…Using TNC as an exemplar perturbant, this thesis sought to understand how macrophage effector functions such as antigen presentation become enhanced or suppressed within the TME. To achieve this, single-cell RNA sequencing (scRNAseq) was performed on infiltrating myeloid cells derived from syngeneic, orthotopically-engrafted, murine breast tumours that were engineered to express high or low levels of TNC. scRNAseq revealed marked heterogeneity in the intra-tumoural myeloid compartment with 7 distinct subsets observed, 5 of which were macrophages (Mac1-5). …”

Breast cancer patient-derived whole-tumor cell culture model for efficient drug profiling and treatment response prediction by Chen, Xinsong, Sifakis, Emmanouil G., Robertson, Stephanie, Neo, Shi Yong, Jun, Seong-Hwan, Tong, Le, Tay, Apple Hui Min, Lövrot, John, Hellgren, Roxanna, Margolin, Sara, Bergh, Jonas, Foukakis, Theodoros, Lagergren, Jens, Lundqvist, Andreas, Ma, Ran, Hartman, Johan

“…Breast cancer (BC) is a complex disease comprising multiple distinct subtypes with different genetic features and pathological characteristics. …”
Get full text

Multiple signatures of a disease in potential biomarker space : getting the signatures consensus and identification of novel biomarkers by Ow, Ghim Siong, Kuznetsov, Vladimir Andreevich

“…Comparison of the empirical frequency distribution (EFD) with the expected background frequency distribution (BFD) allows dichotomization of statistically novel (SN) and common (SC) gIDs within the tGSS. Results: We identify SN or SC biomarkers for tGSSs obtained from previous studies of high-grade serous ovarian cancer (HG-SOC) and breast cancer (BC). …”
Get full text
Get full text

Differences between neonatal units with high and low rates of breast milk feeding for very preterm babies at discharge: a qualitative study of staff experiences by McLeish, J, Aloysius, A, Gale, C, Quigley, M, Kurinczuk, JJ, Alderdice, F

“…Conclusions: Effective support can be influenced by having a supernumerary post dedicated to infant feeding; strong leadership that champions breast milk feeding and breastfeeding within Family Integrated Care; maintaining accountability by using existing quality improvement tools and accredited standards for neonatal units; and training for the whole multi-disciplinary team that encourages and enables every member of staff to take an appropriate share of responsibility for consistently informing and assisting mothers with expressing and breastfeeding. …”

Investigating the effect of the educational intervention based on the Health Belief Model on the knowledge and beliefs of Yemeni teachers in the use of breast cancer screening: a r... by Noman, Sarah, Elarusy, Nadya Mohamed Elfeturi, Rahman, Hejar Abdul, Ismail, Suriani, Azzani, Meram, Taresh, Sahar Mohammed, Aljaberi, Musheer A.

“…Background: Breast cancer (BC) is the most prevalent cancer among women. …”
Get full text

Novel device for microwave cancer detection by Goh, Chye Ying.

“…Simulations using the HFSS software show good return loss within a useful microwave bandwidth. Experimental validations on breast mimicking phantom material are also performed, demonstrating the effectiveness of the proposed probe for detecting the presence of a tumor.…”
Get full text

The role of POPX2 in the regulation of hippo pathway by Muhammad Bakhait Rahmat

“…Our current study has identified POPX2 as a regulator of LATS1, revealing a novel point of modulation within the Hippo pathway i.e. through LATS dephosphorylation. …”
Get full text
Get full text

Semiparametric regression analysis of clustered survival data with semi-competing risks by Peng, Mengjiao, Xiang, Liming, Wang, Shanshan

“…We further illustrate the practical utility of the method by analyzing data from a multi-institutional study of breast cancer.…”
Get full text
Get full text

Integrating Multi-Cancer Early Detection (MCED) Tests with Standard Cancer Screening: System Dynamics Model Development and Feasibility Testing by Fagery, Mussab, Khorshidi, Hadi A., Wong, Stephen Q., Karanfil, Özge, Emery, Jon, IJzerman, Maarten J.

“…In Australia, established screening protocols for colorectal, breast and cervical cancer have significantly contributed to timely cancer detection. …”
Get full text

Regulation and function of innate-like T cells by Hagel, JP

“…Finally, estimated immune cell fractions within TCGA data revealed that the favourable prognostic association of CD161 across cancers was attributable to multiple CD161-expressing cell types. …”

Active nematics for mechanobiology: patterning and flows in living matter by Bhattacharyya, S

“…</p> <p>Finally, we study breast cancer tumours inside an extracellular matrix as confined active matter. …”

Fluorescent imaging and bio-cellular uptake assessment of gold-near infrared dye conjugated cockle shell calcium carbonate nanoparticles by Kiranda, H.K., Mahmud, R.B., Mahmood, S.K., Zakaria, Z.A.

“…Biocompatibility of Au-CsCaCO3NPs in cultured human breast carcinoma cells MCF-7 and mouse embryonic fibroblast cells NIH3T3 was evaluated using bioassays like Lactate Dehydrogenase LDH and Reactive Oxygen Species ROS for toxic examination. …”
Get full text

Microfluidic studies on flow manipulation to assist metastasis research by Tran, Duc Quang

“…We verify the cell isolation ability using a human breast cancer cell line MDA-MB-231 with a perfect agreement with the microbead results. …”
Get full text

Epithelial-mesenchymal transition of cancer cells using bioengineered hybrid scaffold composed of hydrogel/3D-fibrous framework by Pal, Mintu, Chen, Huizhi, Lee, Bae Hoon, Lee, Justin Yin Hao, Yip, Yun Sheng, Tan, Nguan Soon, Tan, Lay Poh

“…Remarkably, this induction is independent of cancer cell-type as similar results were obtained for breast cancer cells, MDA-MB-231 and gastric cancer cells, MKN74. …”
Get full text
Get full text

Antistaphylococcal and antibiofilm activities of ethanolic extract of Piper cubeba L. by Velu, Selvi

“…extract was assessed on cut-up parts of chicken (breast, wing and drumstick) as natural sanitizer. …”
Get full text

Investigations into high resolution imaging and contouring for diagnostic bio-applications by Valiyambath, Krishnan Mohankumar

“…Cancer is a leading cause of deaths in the world, with lung, breast and colorectal cancers being the top killers. …”
Get full text