Systematic Comparison of CRISPR and shRNA Screens to Identify Essential Genes Using a Graph-Based Unsupervised Learning Model Autor Yulian Ding, Connor Denomy, Andrew Freywald, Yi Pan, Franco J. Vizeacoumar, Frederick S. Vizeacoumar, Fang-Xiang Wu

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A Low-Cost and Portable Smart Instrumentation for Detecting Colorectal Cancer Cells Autor Mohammad Wajih Alam, Khan A. Wahid, Md. Fahmid Islam, Wendy Bernhard, Clarence R. Geyer, Franco J. Vizeacoumar

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Mining the plasma-proteome associated genes in patients with gastro-esophageal cancers for biomarker discovery Autor Frederick S. Vizeacoumar, Hongyu Guo, Lynn Dwernychuk, Adnan Zaidi, Andrew Freywald, Fang-Xiang Wu, Franco J. Vizeacoumar, Shahid Ahmed

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Synthetic lethal interactions of DEAD/H-box helicases as targets for cancer therapy Autor Ananna Bhadra Arna, Hardikkumar Patel, Ravi Shankar Singh, Frederick S. Vizeacoumar, Anthony Kusalik, Andrew Freywald, Franco J. Vizeacoumar, Yuliang Wu

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Homoharringtonine demonstrates a cytotoxic effect against triple-negative breast cancer cell lines and acts synergistically with paclitaxel Autor Riley Plett, Paul Mellor, Stephanie Kendall, S. Austin Hammond, Aren Boulet, Kristine Plaza, Frederick S. Vizeacoumar, Franco J. Vizeacoumar, Deborah H. Anderson

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Generation of a SARS-CoV-2 Reverse Genetics System and Novel Human Lung Cell Lines That Exhibit High Virus-Induced Cytopathology Autor Juveriya Qamar Khan, Megha Rohamare, Karthic Rajamanickam, Kalpana K. Bhanumathy, Jocelyne Lew, Anil Kumar, Darryl Falzarano, Franco J. Vizeacoumar, Joyce A. Wilson

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Genetic interactions reveal the evolutionary trajectories of duplicate genes Autor Benjamin VanderSluis, Jeremy Bellay, Gabriel Musso, Michael Costanzo, Balázs Papp, Franco J Vizeacoumar, Anastasia Baryshnikova, Brenda Andrews, Charles Boone, Chad L Myers

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The EphA2 Receptor Regulates Invasiveness and Drug Sensitivity in Canine and Human Osteosarcoma Cells Autor Evelyn D. Harris, Jessica C. Sharpe, Timothy Strozen, Shabnam Abdi, Maya Kliewer, Malkon G. Sanchez, Natacha S. Hogan, Valerie MacDonald-Dickinson, Franco J. Vizeacoumar, Behzad M. Toosi

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A Drug Repurposing Screen Identifies Fludarabine Phosphate as a Potential Therapeutic Agent for N-MYC Overexpressing Neuroendocrine Prostate Cancers Autor Hussain Elhasasna, Raymond Khan, Kalpana K. Bhanumathy, Frederick S. Vizeacoumar, Prachi Walke, Maricris Bautista, Dinesh K. Dahiya, Vincent Maranda, Hardikkumar Patel, Amrutha Balagopal, Nezeka Alli, Anand Krishnan, Andrew Freywald, Franco J. Vizeacoumar

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An integrated computational and experimental study uncovers FUT9 as a metabolic driver of colorectal cancer Autor Noam Auslander, Chelsea E Cunningham, Behzad M Toosi, Emily J McEwen, Keren Yizhak, Frederick S Vizeacoumar, Sreejit Parameswaran, Nir Gonen, Tanya Freywald, Kalpana K Bhanumathy, Andrew Freywald, Franco J Vizeacoumar, Eytan Ruppin

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MEMO1 binds iron and modulates iron homeostasis in cancer cells Autor Natalia Dolgova, Eva-Maria E Uhlemann, Michal T Boniecki, Frederick S Vizeacoumar, Anjuman Ara, Paria Nouri, Martina Ralle, Marco Tonelli, Syed A Abbas, Jaala Patry, Hussain Elhasasna, Andrew Freywald, Franco J Vizeacoumar, Oleg Y Dmitriev

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Integration of cancer-related genetic landscape of Eph receptors and ephrins with proteomics identifies a crosstalk between EPHB6 and EGFR Autor Glinton Hanover, Frederick S. Vizeacoumar, Sara L. Banerjee, Raveena Nair, Renuka Dahiya, Ana I. Osornio-Hernandez, Alain Morejon Morales, Tanya Freywald, Juha P. Himanen, Behzad M. Toosi, Nicolas Bisson, Franco J. Vizeacoumar, Andrew Freywald

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Highly Specific Sigma Receptor Ligands Exhibit Anti-Viral Properties in SARS-CoV-2 Infected Cells Autor David A. Ostrov, Andrew P. Bluhm, Danmeng Li, Juveriya Qamar Khan, Megha Rohamare, Karthic Rajamanickam, Kalpana K. Bhanumathy, Jocelyne Lew, Darryl Falzarano, Franco J. Vizeacoumar, Joyce A. Wilson, Marco Mottinelli, Siva Rama Raju Kanumuri, Abhisheak Sharma, Christopher R. McCurdy, Michael H. Norris

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A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities Autor Franco J Vizeacoumar, Roland Arnold, Frederick S Vizeacoumar, Megha Chandrashekhar, Alla Buzina, Jordan T F Young, Julian H M Kwan, Azin Sayad, Patricia Mero, Steffen Lawo, Hiromasa Tanaka, Kevin R Brown, Anastasia Baryshnikova, Anthony B Mak, Yaroslav Fedyshyn, Yadong Wang, Glauber C Brito, Dahlia Kasimer, Taras Makhnevych, Troy Ketela, Alessandro Datti, Mohan Babu, Andrew Emili, Laurence Pelletier, Jeff Wrana, Zev Wainberg, Philip M Kim, Robert Rottapel, Catherine A O'Brien, Brenda Andrews, Charles Boone, Jason Moffat

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