Integration of cancer-related genetic landscape of Eph receptors and ephrins with proteomics identifies a crosstalk between EPHB6 and EGFR

Integration of cancer-related genetic landscape of Eph receptors and ephrins with proteomics identifies a crosstalk between EPHB6 and EGFR

Summary: Eph receptors and their ephrin ligands are viewed as promising targets for cancer treatment; however, targeting them is hindered by their context-dependent functionalities. To circumvent this, we explore molecular landscapes underlying their pro- and anti-malignant activities. Using unbiase...

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Bibliographic Details
Main Authors: Glinton Hanover, Frederick S. Vizeacoumar, Sara L. Banerjee, Raveena Nair, Renuka Dahiya, Ana I. Osornio-Hernandez, Alain Morejon Morales, Tanya Freywald, Juha P. Himanen, Behzad M. Toosi, Nicolas Bisson, Franco J. Vizeacoumar, Andrew Freywald
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:Cell Reports
Subjects:
CP: Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723006812

Internet

http://www.sciencedirect.com/science/article/pii/S2211124723006812

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