A Comprehensive Review on l-Asparaginase and Its Applications
l-asparaginase (LA) catalyzes the degradation of asparagine, an essential amino acid for leukemic cells, into ammonia and aspartate. Owing to its ability to inhibit protein biosynthesis in lymphoblasts, LA is used to treat acute lymphoblastic leukemia (ALL). Different isozymes of this enzyme have be...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Springer
2016
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| Subjects: | |
| Online Access: | http://umpir.ump.edu.my/id/eprint/12747/1/A%20Comprehensive%20Review%20on%20l-Asparaginase%20and%20Its%20Applications.pdf |