Neuroprotective Effect from Stem Bark Extracts of Knema Laurina Against H2O2-and Aβ1-42-induced Cell Death in Human SH-SY5Y Cells

Neuroprotective Effect from Stem Bark Extracts of Knema Laurina Against H2O2-and Aβ1-42-induced Cell Death in Human SH-SY5Y Cells

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The stem bark extracts of Knema laurina inhibited the hydrogen peroxide (H2O2)- and aggregated amyloid b-peptide 1 –42 length (Ab1 – 42)-induced cell death in differentiated SH-SY5Y cells. Exposure of 250mM H2O2 or 20 mM Ab1 – 42 to the cells for 24 h reduced 50% of cell viability. Pretreatment of c...

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Bibliographic Details
Main Authors: Norsharina, Ismail, Akhtar, Muhammad Nadeem, Maznah, Ismail, Seema, Zareen, Syed Adnan, Ali Shah, Nordin, Hj Lajis, Saiful Nizam, Tajuddin
Format: Article
Language:English
Published: Taylor & Francis 2015
Subjects:
Q Science (General)
Online Access:http://umpir.ump.edu.my/id/eprint/16897/1/fist-2015-sharina-Neuroprotective%20effect1.pdf

Internet

http://umpir.ump.edu.my/id/eprint/16897/1/fist-2015-sharina-Neuroprotective%20effect1.pdf

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