Colchicine Prodrugs and Codrugs: Chemistry and Bioactivities
Antimitotic colchicine possesses low therapeutic index due to high toxicity effects in non-target cell. However, diverse colchicine analogs have been derivatized as intentions for toxicity reduction and structure-activity relationship (SAR) studying. Hybrid system of colchicine structure with nont...
| Główni autorzy: | , , , , , |
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| Format: | Artykuł |
| Język: | English |
| Wydane: |
Elsevier
2018
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| Hasła przedmiotowe: | |
| Dostęp online: | http://umpir.ump.edu.my/id/eprint/19831/8/fist-2017-kwok-Colchicine%20prodrugs%20and%20codrugs1.pdf |