Lyophilized amorphous dispersion of telmisartan in a combined carrier−alkalizer system: formulation development and in vivo study

Lyophilized amorphous dispersion of telmisartan in a combined carrier−alkalizer system: formulation development and in vivo study

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Telmisartan suffers from low oral bioavailability due to its poor water solubility. The research work presents a formulation of solid dispersed (SD) telmisartan formulation as a ternary mixture of a drug, a polymeric carrier (poly-vinylpyrrolidone) (PVP) K30), and an alkalizer (Na2CO3). The preparat...

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Detalhes bibliográficos
Main Authors: AL-japairai, Khater Ahmed Saeed, Alkhalidi, Hala M., Mahmood, Syed, Almurisi, Samah Hamed, Doolaanea, Abd Almonem, Al-Sindi, Taha A., Chatterjee, Bappaditya
Formato: Artigo
Idioma:English
Publicado em: American Chemical Society 2020
Assuntos:
Q Science (General)
Acesso em linha:http://umpir.ump.edu.my/id/eprint/31657/1/Lyophilized%20Amorphous%20Dispersion%20of%20Telmisartan%20in%20a%20Combined.pdf

Internet

http://umpir.ump.edu.my/id/eprint/31657/1/Lyophilized%20Amorphous%20Dispersion%20of%20Telmisartan%20in%20a%20Combined.pdf

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