Prediction of blood-brain barrier permeability of compounds by machine learning algorithms
In the drug development for the Central Nervous System (CNS), the discovery of the compounds that can pass through the brain across the Blood-Brain Barrier (BBB) is the most challenging assessment. Almost 98% of small molecules are unable to permeate BBB, reducing the pharmacokinetics of the drugs i...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Semarak Ilmu Publishing
2024
|
| Subjects: | |
| Online Access: | http://umpir.ump.edu.my/id/eprint/39985/1/Prediction%20of%20blood-brain%20barrier%20permeability%20of%20compounds%20by%20machine.pdf |