Production of Pravastatin by Filamentous Fungi Isolated from Soil
Pravastatin is a clinically useful cholesterol-lowering agent, selectively inhibiting 3-hydroxy-3-methylglutaryl-coenzyme A reductase, the regulatory enzyme in cholesterol biosynthesis. Currently, industrial production of this statin is based on a two-step fermentation process: the initial productio...
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| Format: | Thesis |
| Language: | English |
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2013
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| Online Access: | http://umpir.ump.edu.my/id/eprint/7293/1/CD7797.pdf |