Synthesis of N'-Substituted-2-((5-(4-Chlorophenyl)-1,3,4-Oxadiazol-2-ylthio Acetohydrazie Derivatives as Suitable Antibacterial Agents

Purpose: To evaluate antibacterial activity of a series of molecules bearing 1,3,4-oxadiazole and azomethine moieties. Methods: The 4-chlorobenzoic acid (1) was precursor to N'-substituted-2-(5-(4-chlorophenyl)-1,3,4- oxadiazol-2-ylthio)acetohydrazide, 8a-p, through a multistep synthesis of co...

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Bibliographic Details
Main Authors: Akhtar, Muhammad Nadeem, Rasool, Shahid, Rehman, Aziz-ur, Abbasi, Muhammad Athar
Format: Article
Language:English
Published: Pharmacotherapy Group 2015
Subjects:
Online Access:http://umpir.ump.edu.my/id/eprint/7997/1/fist-2015-nadeem-Synthesis%20of%20N-Substituted.pdf