The niche-derived glial cell line-derived neurotrophic factor (GDNF) induces migration of mouse spermatogonial stem/progenitor cells.

In mammals, the biological activity of the stem/progenitor compartment sustains production of mature gametes through spermatogenesis. Spermatogonial stem cells and their progeny belong to the class of undifferentiated spermatogonia, a germ cell population found on the basal membrane of the seminifer...

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Bibliographic Details
Main Authors: Lisa Dovere, Stefania Fera, Margherita Grasso, Dante Lamberti, Cesare Gargioli, Barbara Muciaccia, Anna Maria Lustri, Mario Stefanini, Elena Vicini
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3632550?pdf=render