Linkage disequilibrium in wild mice.

Crosses between laboratory strains of mice provide a powerful way of detecting quantitative trait loci for complex traits related to human disease. Hundreds of these loci have been detected, but only a small number of the underlying causative genes have been identified. The main difficulty is the ex...

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Bibliographic Details
Main Authors: Cathy C Laurie, Deborah A Nickerson, Amy D Anderson, Bruce S Weir, Robert J Livingston, Matthew D Dean, Kimberly L Smith, Eric E Schadt, Michael W Nachman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-08-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC1950958?pdf=render