TLR4 and pSTAT3 Expression on Circulating Tumor Cells (CTCs) and Immune Cells in the Peripheral Blood of Breast Cancer Patients: Prognostic Implications

TLR4 and pSTAT3 Expression on Circulating Tumor Cells (CTCs) and Immune Cells in the Peripheral Blood of Breast Cancer Patients: Prognostic Implications

TLR4 and pSTAT3 are key players in cancer inflammation and immune evasion; however, their role in the peripheral blood (PB) is largely unexplored. Herein we evaluated their expression in the circulating tumor cells (CTCs) and peripheral-blood mononuclear cells (PBMCs) of patients with early (<i&g...

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Bibliographic Details
Main Authors: Maria A. Papadaki, Alexia Monastirioti, Christina A. Apostolopoulou, Despoina Aggouraki, Chara Papadaki, Kleita Michaelidou, Maria Vassilakopoulou, Katerina Alexakou, Dimitrios Mavroudis, Sofia Agelaki
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Cancers
Subjects:
toll-like receptor 4 (TLR4)
phosphorylated signal transducer and activator of transcription protein 3 (pSTAT3)
circulating tumor cells (CTCs)
peripheral-blood mononuclear cells (PBMCs)
immune cells
breast cancer
Online Access:https://www.mdpi.com/2072-6694/14/4/1053

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https://www.mdpi.com/2072-6694/14/4/1053

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