Engineering protein translocation pathway to improve recombinant proteins in Pichia pastoris

Engineering protein translocation pathway to improve recombinant proteins in Pichia pastoris

Pichia pastoris is one of the most commonly used hosts for producing heterologous proteins, whereas production levels vary depending on the protein of interest and are also regulated by regulatory factors. We conducted RNA-seq by expressing the reporter EGFP and observed significant upregulation of...

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Bibliographic Details
Main Authors: Shengyan Wang, Huijia Dai, Qingling Tang, Yujing Yu, Yaying Xie, Tao Wang, Yide Huang
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Current Research in Biotechnology
Subjects:
Pichia pastoris
Sec complex
Secretion pathway
Heterologous expression
Online Access:http://www.sciencedirect.com/science/article/pii/S259026282400008X

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http://www.sciencedirect.com/science/article/pii/S259026282400008X

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