Adaptation of SIVmac to baboon primary cells results in complete absence of in vivo baboon infectivity

Adaptation of SIVmac to baboon primary cells results in complete absence of in vivo baboon infectivity

While simian immunodeficiency virus (SIV) infection is non-pathogenic in naturally infected African nonhuman primate hosts, experimental or accidental infection in rhesus macaques often leads to AIDS. Baboons, widely distributed throughout Africa, do not naturally harbor SIV, and experimental infect...

Full description

Bibliographic Details
Main Authors: Veronica Obregon-Perko, Amanda Mannino, Jason T. Ladner, Vida Hodara, Diako Ebrahimi, Laura Parodi, Jessica Callery, Gustavo Palacios, Luis D. Giavedoni
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-06-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
viral adaptive changes and evolution
simian immunodeficiency virus (SIV)
baboon
innate immunity
chronic infection
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2024.1408245/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2024.1408245/full

Similar Items