miRNA-mediated loss of m6A increases nascent translation in glioblastoma.

miRNA-mediated loss of m6A increases nascent translation in glioblastoma.

Within the glioblastoma cellular niche, glioma stem cells (GSCs) can give rise to differentiated glioma cells (DGCs) and, when necessary, DGCs can reciprocally give rise to GSCs to maintain the cellular equilibrium necessary for optimal tumor growth. Here, using ribosome profiling, transcriptome and...

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Detalles Bibliográficos
Main Authors: John P Zepecki, David Karambizi, J Eduardo Fajardo, Kristin M Snyder, Charlotte Guetta-Terrier, Oliver Y Tang, Jia-Shu Chen, Atom Sarkar, Andras Fiser, Steven A Toms, Nikos Tapinos
Formato: Artigo
Idioma:English
Publicado: Public Library of Science (PLoS) 2021-03-01
Series:PLoS Genetics
Acceso en liña:https://doi.org/10.1371/journal.pgen.1009086

Internet

https://doi.org/10.1371/journal.pgen.1009086

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