miRNA-mediated loss of m6A increases nascent translation in glioblastoma.

miRNA-mediated loss of m6A increases nascent translation in glioblastoma.

Within the glioblastoma cellular niche, glioma stem cells (GSCs) can give rise to differentiated glioma cells (DGCs) and, when necessary, DGCs can reciprocally give rise to GSCs to maintain the cellular equilibrium necessary for optimal tumor growth. Here, using ribosome profiling, transcriptome and...

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Bibliographic Details
Main Authors: John P Zepecki, David Karambizi, J Eduardo Fajardo, Kristin M Snyder, Charlotte Guetta-Terrier, Oliver Y Tang, Jia-Shu Chen, Atom Sarkar, Andras Fiser, Steven A Toms, Nikos Tapinos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-03-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1009086

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https://doi.org/10.1371/journal.pgen.1009086

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