Post-translational regulation of Oct4 transcriptional activity.

Oct4 is a key component of the molecular circuitry which regulates embryonic stem cell proliferation and differentiation. It is essential for maintenance of undifferentiated, pluripotent cell populations, and accomplishes these tasks by binding DNA in multiple heterodimer and homodimer configuration...

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Manylion Llyfryddiaeth
Prif Awduron: Jonathan P Saxe, Alexey Tomilin, Hans R Schöler, Kathrin Plath, Jing Huang
Fformat: Erthygl
Iaith:English
Cyhoeddwyd: Public Library of Science (PLoS) 2009-01-01
Cyfres:PLoS ONE
Mynediad Ar-lein:http://europepmc.org/articles/PMC2637973?pdf=render