Generation of proximal tubule spheroids for nephrotoxicity assessment
Background To date, nephrotoxicity in new drug development has been evaluated through two-dimensional culture of representative cell lines, such as HK-2 and human proximal tubule epithelial cells (hPTECs). Approximately 20% of new drugs that were safe in preclinical studies were withdrawn from clini...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
The Organoid Society
2022-10-01
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| Series: | Organoid |
| Subjects: | |
| Online Access: | http://j-organoid.org/upload/pdf/organoid-2022-2-e30.pdf |