The Netrin-related domain of Sfrp1 interacts with Wnt ligands and antagonizes their activity in the anterior neural plate

<p>Abstract</p> <p>Background</p> <p>Secreted frizzled related proteins (SFRPs) are multifunctional modulators of Wnt and BMP (Bone Morphogenetic Protein) signalling necessary for the development of most organs and the homeostasis of different adult tissues. SFRPs fold...

Full description

Bibliographic Details
Main Authors: Esteve Pilar, Lopez-Rios Javier, Ruiz Jose, Bovolenta Paola
Format: Article
Language:English
Published: BMC 2008-08-01
Series:Neural Development
Online Access:http://www.neuraldevelopment.com/content/3/1/19