Role of pyroptosis in spinal cord injury and its therapeutic implications

Role of pyroptosis in spinal cord injury and its therapeutic implications

Background: Currently, spinal cord injury (SCI) is a pathological incident that triggers several neuropathological conditions, leading to the initiation of neuronal damage with several pro-inflammatory mediators' release. However, pyroptosis is recognized as a new programmed cell death mechanis...

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Bibliographic Details
Main Authors: Abdullah Al Mamun, Yanqing Wu, Ilma Monalisa, Chang Jia, Kailiang Zhou, Fahad Munir, Jian Xiao
Format: Article
Language:English
Published: Elsevier 2021-02-01
Series:Journal of Advanced Research
Subjects:
Spinal cord injury
Neuroinflammation
Pyroptosis
NLRP3
Caspase-1
Therapeutic implications
Online Access:http://www.sciencedirect.com/science/article/pii/S2090123220301880

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http://www.sciencedirect.com/science/article/pii/S2090123220301880

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