Antisense Oligonucleotide Technologies to Combat Obesity and Fatty Liver Disease

Synthetic oligonucleotide technologies are DNA or RNA based molecular compounds that are utilized to disrupt gene transcription or translation in target tissues or cells. Optimally, oligonucleotides are 10–30 base pairs in length, and mediate target gene suppression through directed sequence homolog...

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Bibliographic Details
Main Authors: Michael F. Keating, Brian G. Drew, Anna C. Calkin
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2022.839471/full