Ex vivo expanded allogeneic natural killer cells have potent cytolytic activity against cancer cells through different receptor-ligand interactions

Ex vivo expanded allogeneic natural killer cells have potent cytolytic activity against cancer cells through different receptor-ligand interactions

Abstract Background Recently, allogeneic natural killer (NK) cells have gained considerable attention as promising immunotherapeutic tools due to their unique biological functions and characteristics. Although many NK expansion strategies have been reported previously, a deeper understanding of cryo...

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Bibliographic Details
Main Authors: Daun Jung, Young Seok Baek, In Jee Lee, Ki Yeon Kim, Heejoo Jang, Sohyun Hwang, Jieun Jung, Yong-wha Moon, Kyung-Soon Park, Yong-Soo Choi, Hee Jung An
Format: Article
Language:English
Published: BMC 2021-10-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Natural killer cells
NK-activating receptors
Inhibitory receptors
Allogeneic
Cryopreservation
cancer immunotherapy
Online Access:https://doi.org/10.1186/s13046-021-02089-0

Internet

https://doi.org/10.1186/s13046-021-02089-0

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