Genotype and phenotype analysis of α-thalassemia fusion gene in southern China

Genotype and phenotype analysis of α-thalassemia fusion gene in southern China

Objective The α-globin fusion gene between the HBA2 and HBAP1 genes, is clinically important in thalassemia screening because this fusion gene can cause severe hemoglobin (Hb) H disease when combined with α0 -thalassemia (α0 -thal). In this study, we evaluate the red blood cell parameters of α-thala...

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Bibliographic Details
Main Authors: Yi-Yuan Ge, Yan-Quan Lai, Ai-Ping Ju, Lie-Jun Li, Min Lu, Long-Xu Xie, Min Huang, Li-Ye Yang
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Hematology
Subjects:
Thalassemia
gene testing
genotype
China
HBA2
α-globin gene fusion
Online Access:https://www.tandfonline.com/doi/10.1080/16078454.2024.2399361

Internet

https://www.tandfonline.com/doi/10.1080/16078454.2024.2399361

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