Effects of cIAP-1, cIAP-2 and XIAP triple knockdown on prostate cancer cell susceptibility to apoptosis, cell survival and proliferation

<p>Abstract</p> <p>Background</p> <p>Manipulating apoptotic resistance represents an important strategy for the treatment of hormone refractory prostate cancer. We hypothesised that the Inhibitor of Apoptosis (IAP) Proteins may be mediating this resistance and knockdown...

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Detaylı Bibliyografya
Asıl Yazarlar: Dowling Catherine, Gill Catherine, O'Neill Amanda J, Watson R William G
Materyal Türü: Makale
Dil:English
Baskı/Yayın Bilgisi: BMC 2009-06-01
Seri Bilgileri:Molecular Cancer
Online Erişim:http://www.molecular-cancer.com/content/8/1/39