Comparison of airway responses in sheep of different age in precision-cut lung slices (PCLS).

Animal models should display important characteristics of the human disease. Sheep have been considered particularly useful to study allergic airway responses to common natural antigens causing human asthma. A rationale of this study was to establish a model of ovine precision-cut lung slices (PCLS)...

Full description

Bibliographic Details
Main Authors: Verena A Lambermont, Marco Schlepütz, Constanze Dassow, Peter König, Luc J Zimmermann, Stefan Uhlig, Boris W Kramer, Christian Martin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4167544?pdf=render