Structural Basis of VSIG3: The Ligand for VISTA

Structural Basis of VSIG3: The Ligand for VISTA

B7 family members and their receptors play key roles in regulating T cell responses, and constitute very attractive targets for developing immunotherapeutic drugs. V-Set and Immunoglobulin domain containing 3 (VSIG3), a ligand for the novel B7 family immune checkpoint V-domain immunoglobulin suppres...

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Bibliographic Details
Main Authors: Xiaoxue Xie, Caiping Chen, Wenting Chen, Jingwei Jiang, Lanlan Wang, Tingting Li, Hongbin Sun, Jun Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Immunology
Subjects:
VISTA
VSIG3
X-ray
crystal structure
drug discovery
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.625808/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.625808/full

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