Macrophage diversity in human cancers: New insight provided by single-cell resolution and spatial context

Macrophage diversity in human cancers: New insight provided by single-cell resolution and spatial context

M1/M2 paradigm of macrophage plasticity has existed for decades. Now it becomes clear that this dichotomy doesn't adequately reflect the diversity of macrophage phenotypes in tumor microenvironment (TME). Tumor-associated macrophages (TAMs) are a major population of innate immune cells in the T...

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Bibliographic Details
Main Authors: Militsa Rakina, Irina Larionova, Julia Kzhyshkowska
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Heliyon
Subjects:
Tumor-associated macrophages
Subpopulation
Phenotype
Plasticity
Diversity
Spatial transcriptomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024043639

Internet

http://www.sciencedirect.com/science/article/pii/S2405844024043639

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