Identification of functional pathways for regenerative bioactivity of selected renal cells

Abstract Background Selected renal cells (SRC) are in Phase II clinical trials as a kidney-sourced, autologous, tubular epithelial cell-enriched cell-based therapy for chronic kidney disease (CKD). In preclinical studies with rodent models of CKD, SRC have been shown to positively modulate key renal...

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Bibliographic Details
Main Authors: Wei Sha, Timothy Bertram, Deepak Jain, Cory Brouwer, Joydeep Basu
Format: Article
Language:English
Published: BMC 2022-02-01
Series:Stem Cell Research & Therapy
Subjects:
Online Access:https://doi.org/10.1186/s13287-022-02713-6