Acute antioxidant and cytoprotective effects of sulforaphane in brain endothelial cells and astrocytes during inflammation and excitotoxicity

Acute antioxidant and cytoprotective effects of sulforaphane in brain endothelial cells and astrocytes during inflammation and excitotoxicity

Abstract Sulforaphane (SFN), a bioactive phytochemical isothiocyanate, has a wide spectrum of cytoprotective effects that involve induction of antioxidant genes. Nongenomic antioxidant effects of SFN have not been investigated. Brain oxidative stress during inflammation and excitotoxicity leads to n...

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Bibliographic Details
Main Authors: Jianxiong Liu, Giri K. Chandaka, Rong Zhang, Helena Parfenova
Format: Article
Language:English
Published: Wiley 2020-08-01
Series:Pharmacology Research & Perspectives
Subjects:
antioxidants
apoptosis
astrocytes
endothelial cells
excitotoxicity
inflammation
Online Access:https://doi.org/10.1002/prp2.630

Internet

https://doi.org/10.1002/prp2.630

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