Concepts for New Rapid Simple HPLC Method for Quantification of Fosfomycin Trometamol in Pharmaceutical Dosage Forms with Direct UV Detection

Concepts for New Rapid Simple HPLC Method for Quantification of Fosfomycin Trometamol in Pharmaceutical Dosage Forms with Direct UV Detection

Two different concepts for developing direct HPLC-UV methods for quantifying fosfomycin trometamol were developed without any derivatization and modification of the analyte. In the first concept, without the use of alkylamines as ion-pairs in the mobile phase, by using cyanopropyl CN and a strong an...

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Bibliographic Details
Main Authors: Marjan Piponski, Tanja Bakovska Stoimenova, Tetiana Melnyk, Sergiy Kovalenko, Elena Lazarevska Todevska, Marjan Velkovski, Sami El Deeb, Yuriy Mysula, Liliya Logoyda
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Scientia Pharmaceutica
Subjects:
amines
ion-pairing
HPLC
fosfomycin trometamol
Online Access:https://www.mdpi.com/2218-0532/90/2/35

Internet

https://www.mdpi.com/2218-0532/90/2/35

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