Effect of increased positive end-expiratory pressure on intracranial pressure and cerebral oxygenation: impact of respiratory mechanics and hypovolemia
Abstract Background To evaluate the impact of positive end-expiratory pressure (PEEP) on intracranial pressure (ICP) in animals with different respiratory mechanics, baseline ICP and volume status. Methods A total of 50 male adult Bama miniature pigs were involved in four different protocols (n = 20...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-11-01
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Series: | BMC Neuroscience |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12868-021-00674-9 |