Effect of increased positive end-expiratory pressure on intracranial pressure and cerebral oxygenation: impact of respiratory mechanics and hypovolemia

Abstract Background To evaluate the impact of positive end-expiratory pressure (PEEP) on intracranial pressure (ICP) in animals with different respiratory mechanics, baseline ICP and volume status. Methods A total of 50 male adult Bama miniature pigs were involved in four different protocols (n = 20...

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Bibliographic Details
Main Authors: Han Chen, Xiao-Fen Zhou, Da-Wei Zhou, Jian-Xin Zhou, Rong-Guo Yu
Format: Article
Language:English
Published: BMC 2021-11-01
Series:BMC Neuroscience
Subjects:
Online Access:https://doi.org/10.1186/s12868-021-00674-9