In Vitro Inhibition of Renal OCT2 and MATE1 Secretion by Antiemetic Drugs
The organic cation transporter 2 (OCT2) and multidrug and toxin extrusion protein 1 (MATE1) mediate the renal secretion of drugs. Recent studies suggest that ondansetron, a 5-HT<sub>3</sub> antagonist drug used to prevent nausea and vomiting, can inhibit OCT2- and MATE1-mediated transpor...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-06-01
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| Series: | International Journal of Molecular Sciences |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1422-0067/22/12/6439 |